CFam Chemical Families Database
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Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM1633
Family Name cGMP-inhibited 3',5'-cyclic phosphodiesterase B and cGMP-inhibited 3',5'-cyclic phosphodiesterase A inhibitor 7-[4-(4-benzylpiperazin-1-yl)-4-oxobutoxy]-1,3-dihydroimidazo[4,5-b]quinolin-2-one family
No. of Seeds 39 No. of Other Members 10
Family Centroid CFAMM00325906 Functional Category Bioactive with Natural Product
Superfamily cGMP-inhibited 3',5'-cyclic phosphodiesterase B and cGMP-inhibited 3',5'-cyclic phosphodiesterase A Binder Superfamily
Class Class 976

Cousin Family NamesSeedsMembers
Histamine H1 receptor Ligand Astemizole Family 7 240
cGMP-specific 3',5'-cyclic phosphodiesterase inhibitor indole... 28 2712
Epidermal growth factor receptor Ligand Gefitinib Family 26 600
Corticotropin-releasing factor receptor 1 Ligand CRF-1 Antagon... 29 421
Receptor tyrosine-protein kinase erbB-2 Inhibitor CP-724714 Fa... 4 180
Vascular endothelial growth factor receptor 2 Ligand Cediranib... 8 38
Platelet-derived growth factor receptor Ligand CP-868596 Family 3 91
Insulin-like growth factor 1 receptor Ligand AEW-541 Family 12 140
Receptor tyrosine-protein kinase erbB-2 Inhibitor TAK-285 Family 16 124
Corticotropin-releasing factor receptor 1 Ligand GW876008 Family 3 30
SB1518 family 7 103
RAF proto-oncogene serine/threonine-protein kinase Inhibitor R... 7 148
Protein kinase C theta type Inhibitor 4-(1h-indol-5-yloxy)-5-s... 21 194
DNA Binder Bisbenzimide (hoechst 33258) Family 4 159
Peptide deformylase, mitochondrial Inhibitor Epiroprim Family 5 68
Tyrosine kinase Inhibitor PKI166 Family 17 198
Cyclin-dependent kinase 1 and Cyclin-dependent kinase 2 Inhibi... 1 8
Heat shock protein HSP 90-alpha Inhibitor 8-benzo[1,3]dioxol-,... 5 83
Gamma-aminobutyric acid receptor subunit alpha-1 and Gamma-ami... 13 22
Poly [ADP-ribose] polymerase 1 Inhibitor 2-(3'-methoxyphenyl) ... 9 93
Angiopoietin-1 receptor and Tyrosine-protein kinase Lck Inhibi... 3 64
Cyclin-dependent kinase 2 and Cyclin-dependent kinase 9 Inhibi... 10 35
D(2) dopamine receptor and D(3) dopamine receptor Ligand [2-(1... 17 100
Serine/threonine-protein kinase Chk2 Inhibitor 5-nitro-2-(4-ph... 6 3
Glutamate receptor ionotropic, NMDA 2B and Glutamate receptor ... 3 23
cGMP-inhibited 3',5'-cyclic phosphodiesterase A Inhibitor 7-et... 7 57
Cytochrome P450 2D6 and Cytochrome P450 3A4 Inhibitor 2-[3-(4-... 7 128
Adenosine receptor A1 and Adenosine receptor A3 Ligand 2-(4-me... 3 23
Glycogen synthase kinase-3 beta and Mitogen-activated protein ... 8 8
Adenosine receptor A1 and Adenosine receptor A2a Ligand 2-(3''... 2 3
TGF-beta receptor type-1 Ligand SB-431542 Family 2 42
Fatty-acid amide hydrolase 1 Inhibitor BMS-1 Family 5 22
Epidermal growth factor receptor Ligand 4-(5-bromoindole-3-yl)... 6 15
Reverse transcriptase Inhibitor Atevirdine Family 4 55
Reverse transcriptase Inhibitor UK-129485 Family 23 221
Sodium channel protein type 5 subunit alpha Ligand Enecadin Fa... 1 11
Delta-type opioid receptor and Kappa-type opioid receptor Liga... 10 46
Delta-type opioid receptor and Mu-type opioid receptor Ligand ... 18 72
cGMP-specific 3',5'-cyclic phosphodiesterase Inhibitor SK&F-96... 5 83
Sodium-dependent serotonin transporter and 5-hydroxytryptamine... 3 4
Alpha-1B adrenergic receptor and Alpha-1D adrenergic receptor ... 6 35
Serine/threonine-protein kinase B-raf inhibitor SureCN1015955 ... 17 18
Vascular endothelial growth factor receptor 2 and Angiopoietin... 2 11
Histamine H4 receptor ligand AGN-PC-07ZG9H family 4 4
Angiopoietin-1 receptor and Aurora kinase B ligand SureCN97387... 4 1
cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10... 6 11
Sphingosine 1-phosphate receptor 1 and Sphingosine 1-phosphate... 7 16
Beta-1 adrenergic receptor and Beta-2 adrenergic receptor liga... 4 18
Beta-1 adrenergic receptor and Beta-2 adrenergic receptor liga... 6 7
Lysine--tRNA ligase and Dual specificity protein kinase CLK4 i... 4 27
cGMP-inhibited 3',5'-cyclic phosphodiesterase B and cGMP-inhib... 9 3
cGMP-inhibited 3',5'-cyclic phosphodiesterase B and cGMP-inhib... 7 5
Cathepsin S and Cathepsin K inhibitor SureCN1629664 family 10 11
Cathepsin S and Cathepsin K inhibitor AGN-PC-07YOWS family 4 6
Aurora kinase A inhibitor SureCN761545 family 2 2
Adenosine receptor A3 and Adenosine receptor A2a ligand 4-(5-b... 2 5
5-hydroxytryptamine receptor 1D and 5-hydroxytryptamine recept... 9 19
Angiopoietin-1 receptor and Aurora kinase B ligand SureCN12658... 3 19
Vascular endothelial growth factor receptor 2 ligand AGN-PC-09... 5 11
Glucocorticoid receptor ligand (2R)-1,1,1-trifluoro-4-(2-metho... 2 5
Casein kinase I isoform delta and Mitogen-activated protein ki... 3 18
Adenosine receptor A2b and Adenosine receptor A1 ligand SureCN... 52 12
cGMP-specific 3',5'-cyclic phosphodiesterase inhibitor SureCN6... 19 11
cGMP-specific 3',5'-cyclic phosphodiesterase inhibitor SureCN6... 8 12
DNA-(apurinic or apyrimidinic site) lyase and Retinal dehydrog... 1 3
cGMP-specific 3',5'-cyclic phosphodiesterase inhibitor CHEMBL2... 3 8
Adenosine receptor A2b and Adenosine receptor A1 ligand MRS 17... 10 0
Melatonin receptor type 1A ligand N-[2-(5-methoxy-2-phenyl-1H-... 1 2
Thyroid hormone receptor beta and Ferritin light chain ligand ... 1 35
Cellular tumor antigen p53 and Prelamin-A/C inhibitor CHEMBL14... 2 11
Dual specificity tyrosine-phosphorylation-regulated kinase 1A ... 3 20
D(3) dopamine receptor and D(2) dopamine receptor ligand 2-[4-... 2 3
D(3) dopamine receptor and D(2) dopamine receptor ligand SureC... 5 4
Thyroid hormone receptor beta and Cruzipain ligand CHEMBL14730... 1 12
Cellular tumor antigen p53 and Lysosomal alpha-glucosidase inh... 1 6
Epidermal growth factor receptor ligand Pyrimido[4,5-b]indole ... 1 4
Tyrosine-protein kinase JAK2 inhibitor 5-(3-methoxyphenyl)-N-[... 2 11
Melanocortin receptor 4 ligand AGN-PC-076AML family 3 24
Neuropeptide Y receptor type 5 ligand 3-[2-[6-[2-[(2-methylpro... 1 0
cGMP-specific 3',5'-cyclic phosphodiesterase inhibitor SureCN6... 2 4
Prostaglandin D2 receptor ligand 2-methoxy-N-[2-(4-methoxyphen... 2 5
Cannabinoid receptor 2 and Cannabinoid receptor 1 ligand AGN-P... 2 2
Adenosine receptor A3 ligand AGN-PC-08WSLM family 5 22
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subun... 6 12
Coagulation factor X and Cationic trypsin inhibitor AGN-PC-075... 26 7
Insulin-like growth factor 1 receptor ligand 3qqu family 2 12
Melanin-concentrating hormone receptor 1 ligand SureCN3334861 ... 1 3
Cholecystokinin receptor type A ligand AGN-PC-0A9ULH family 8 8
Integrin alpha-V and Integrin beta-5 inhibitor SureCN2491273 f... 11 10
Melatonin receptor type 1B ligand CHEMBL1802020 family 2 7
Melatonin receptor type 1B and Melatonin receptor type 1A liga... 1 0
Insulin-like growth factor 1 receptor and Potassium voltage-ga... 2 2
Tyrosine-protein kinase JAK2 inhibitor (2S)-1-[4-[4-[[7-(2-met... 11 27
Acyl-CoA desaturase 1 and Acyl-CoA desaturase inhibitor 2-[4-[... 2 6
Corticotropin-releasing factor receptor 1 ligand Pyridopyrazin... 2 1
Histamine H1 receptor and Histamine H4 receptor ligand 1H-benz... 2 7
Scavenger receptor class B member 1 ligand methyl 9-[3-(4,6-di... 2 10
Serine/threonine-protein kinase pim-1 and Serine/threonine-pro... 4 9
cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10... 6 0
cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10... 8 1
cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10... 10 4
MAP kinase-activated protein kinase 2 inhibitor N-[4-(4-oxospi... 3 0
cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10... 8 2
Corticotropin-releasing factor receptor 1 and Corticotropin-re... 2 1
Hepatocyte growth factor receptor and Cytochrome P450 3A4 liga... 5 2
Interleukin-1 receptor-associated kinase 4 and Interleukin-1 r... 4 0
Macrophage colony-stimulating factor 1 receptor and Ephrin typ... 1 0
Vascular endothelial growth factor receptor 2 ligand AGN-PC-00... 8 1
Serine/threonine-protein kinase B-raf and RAF proto-oncogene s... 1 0
Histamine H3 receptor ligand AGN-PC-075YXY family 1 4
Serine/threonine-protein kinase TBK1 and Inhibitor of nuclear ... 8 6
cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10... 3 6
Cannabinoid receptor 1 and Cannabinoid receptor 2 ligand 2-[4-... 1 2
Histamine H3 receptor and Cytochrome P450 2D6 ligand AGN-PC-07... 1 0
Smoothened homolog inhibitor N-[3-(1H-benzimidazol-2-yl)phenyl... 2 1
Serine/threonine-protein kinase Chk1 inhibitor SureCN6387344 f... 6 11
Dual specificity protein kinase TTK inhibitor 6-N-cyclohexyl-2... 12 2
Dual specificity protein kinase TTK inhibitor 2-[1-[4-[[6-(cyc... 8 0
Glycogen synthase kinase-3 beta inhibitor 2-(4-fluorophenyl)-N... 7 3
Vascular endothelial growth factor receptor 2 and Fibroblast g... 1 6
Platelet-derived growth factor receptor alpha and Vascular end... 3 1
Activated CDC42 kinase 1 inhibitor 5-(2-fluorophenyl)-N-[[(2S)... 5 0
RAC-alpha serine/threonine-protein kinase inhibitor 5-[5-[(2S)... 3 1
Growth hormone secretagogue receptor type 1 ligand SureCN36800... 14 42
Glutamate receptor ionotropic, NMDA 1 and Glutamate receptor i... 11 1
Fatty-acid amide hydrolase 1 inhibitor 4-[[3-(4-chlorophenoxy)... 2 7
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subun... 4 0
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subun... 3 0
cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10... 2 0
cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10... 2 1
Histamine H4 receptor ligand AGN-PC-00FEQJ family 2 3
Nitric oxide synthase, inducible inhibitor 2-[1-(2-imidazol-1-... 4 3
Fatty-acid amide hydrolase 1 inhibitor 4-[[3-(4-chlorophenoxy)... 4 2
Glycogen synthase kinase-3 beta and Casein kinase I isoform ga... 3 0
cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10... 3 2
Nitric oxide synthase, inducible inhibitor N-(1,3-benzodioxol-... 11 1
Tyrosine-protein kinase Lck inhibitor 3-[[2-(benzimidazol-1-yl... 2 0
CGMP-dependent protein kinase inhibitor 1-[2-(4-fluorophenyl)-... 1 4
Corticotropin-releasing factor receptor 1 and Corticotropin-re... 3 14
Receptor tyrosine-protein kinase erbB-2 ligand SureCN4461871 f... 2 2
Receptor tyrosine-protein kinase erbB-2 ligand SureCN4463897 f... 3 2
Aromatase inhibitor 2-(imidazol-1-ylmethyl)-6-methoxy-1-phenyl... 2 8
Tyrosine-protein kinase SYK inhibitor N-tert-butyl-2-[5-(diflu... 7 0
Tyrosine-protein kinase JAK3 and Tyrosine-protein kinase JAK2 ... 1 0
Histone-arginine methyltransferase CARM1 inhibitor AGN-PC-00HE... 4 4
Glycogen synthase kinase-3 beta inhibitor 3-imidazo[1,2-a]pyri... 1 1
5-hydroxytryptamine receptor 2C and 5-hydroxytryptamine recept... 2 2
Diacylglycerol O-acyltransferase 1 inhibitor 4-[5-[5-(1H-benzi... 7 1
Orexin receptor type 2 and Orexin receptor type 1 ligand 9-(4,... 2 5
Vascular endothelial growth factor receptor 2 and Angiopoietin... 3 3
Angiopoietin-1 receptor and Vascular endothelial growth factor... 2 0
Fatty acid-binding protein, adipocyte and Fatty acid-binding p... 4 4
Histamine H3 receptor and Sodium-dependent serotonin transport... 2 0
cGMP-specific 3',5'-cyclic phosphodiesterase inhibitor 8-[(6,7... 6 8
Collagenase 3 inhibitor 5-[4-[4-(1H-benzimidazol-2-yl)phenoxy]... 3 0
Collagenase 3 inhibitor 1-[6-[4-(1H-benzimidazol-2-yl)phenoxy]... 3 0
Receptor tyrosine-protein kinase erbB-2 and Epidermal growth f... 9 2
Melanin-concentrating hormone receptor 1 ligand SureCN5431614 ... 1 2
Cathepsin K and Cathepsin S inhibitor SureCN4135077 family 2 0
Melanin-concentrating hormone receptor 1 ligand (1S,3S)-3-N-(7... 2 2
C-X-C chemokine receptor type 3 ligand N-[(1R)-1-[1-(4-ethoxyp... 5 9
Sterol O-acyltransferase 1 inhibitor 1-[4-[2-(4,5-diphenyl-1H-... 1 0
Substance-P receptor ligand N-[(2R)-1-[acetyl-[(2-chlorophenyl... 2 2
Type-1 angiotensin II receptor ligand 2-ethyl-6-methoxy-N-[[4-... 2 0
Insulin-like growth factor 1 receptor ligand 3-[8-amino-1-(4-e... 9 0
Dihydrofolate reductase and Bifunctional dihydrofolate reducta... 5 1
cGMP-inhibited 3',5'-cyclic phosphodiesterase B and cGMP-inhib... 16 0
D(3) dopamine receptor and D(2) dopamine receptor ligand SureC... 4 1
Glucagon receptor ligand SureCN2647807 family 3 7
Gamma-aminobutyric acid receptor subunit pi and GABA theta sub... 3 0
5-hydroxytryptamine receptor 6 ligand 2-[(2Z)-2-[3-[(3-methoxy... 1 11
Cyclin-dependent kinase 1 inhibitor AGN-PC-075VQQ family 2 0
Protein farnesyltransferase/geranylgeranyltransferase type-1 s... 3 1
Calcitonin gene-related peptide type 1 receptor ligand SureCN1... 1 3
Vascular endothelial growth factor receptor 2 ligand 2-aminobe... 2 0
Cyclin-dependent kinase 1 and Receptor tyrosine-protein kinase... 2 3
Histone deacetylase 1 inhibitor (7S)-N-hydroxy-7-[[2-(5-methox... 1 2
Cholecystokinin receptor type A ligand AGN-PC-077L8J family 22 2
Insulin-like growth factor 1 receptor and Mitogen-activated pr... 15 1
Rho-associated protein kinase 2 inhibitor SureCN1519463 family 5 1
Rho-associated protein kinase 2 inhibitor AGN-PC-078WHL family 3 1
Cathepsin S and Cathepsin K inhibitor 2-cyano-pyrropyrimidine,... 4 1
Oxytocin receptor and Vasopressin V1a receptor ligand AGN-PC-0... 4 3
Translocator protein inhibitor AGN-PC-04X3HY family 10 1
Cholecystokinin receptor type A ligand SureCN3132309 family 11 0
Cholecystokinin receptor type A ligand AGN-PC-077KXF family 2 0
Tyrosine-protein kinase SYK and Tyrosine-protein kinase ZAP-70... 3 8
Nociceptin receptor and Delta-type opioid receptor ligand 2-[3... 2 1
Cathepsin S and Cathepsin K inhibitor AGN-PC-078ZDC family 4 2
Platelet-derived growth factor receptor beta and Fibroblast gr... 2 1
cGMP-specific 3',5'-cyclic phosphodiesterase inhibitor AGN-PC-... 3 1
Epidermal growth factor receptor ligand Pyrido[3,4-d]pyrimidin... 3 1
D(2) dopamine receptor ligand AGN-PC-07C1V6 family 2 3
cGMP-specific 3',5'-cyclic phosphodiesterase inhibitor AGN-PC-... 7 6
Histone-arginine methyltransferase CARM1 inhibitor AGN-PC-07CR... 4 0
TGF-beta receptor type-1 ligand SureCN373216 family 3 14
Oxysterols receptor LXR-alpha and Oxysterols receptor LXR-beta... 7 4
D(3) dopamine receptor and D(2) dopamine receptor ligand SureC... 1 0
Gamma-aminobutyric acid receptor subunit pi and GABA theta sub... 2 0
cGMP-inhibited 3',5'-cyclic phosphodiesterase B and cGMP-inhib... 1 1
Lysosomal Pro-X carboxypeptidase inhibitor 4-[6-[(2S)-2-(5,6-d... 2 2
Bifunctional epoxide hydrolase 2 and Arachidonate 5-lipoxygena... 3 0
Fatty-acid amide hydrolase 1 inhibitor bisarylimidazole deriva... 1 1
Metabotropic glutamate receptor 5 ligand 2-[4-(4-fluoro-3-meth... 1 0
Multidrug resistance-associated protein 1 inhibitor SureCN6823... 1 0
Beta-lactamase and Microtubule-associated protein tau inhibito... 1 1
Neuropeptide Y receptor type 5 ligand 7-methoxy-2-methyl-6-phe... 1 1
Putative NP ZINC40310254 Family 74 1


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00325903 CHEMBL316367 Bioactive 7-[4-oxo-4-[4-(2-oxo-2-pyrrolidin-1-ylethyl)piperazin-1-yl]butoxy]-1,3-dihydroimidazo[4,5-b]quinolin-2-one
CFAMM00325867 CHEMBL90380 Bioactive 7-[4-(4-benzhydrylpiperazin-1-yl)-4-oxobutoxy]-1,3-dihydroimidazo[4,5-b]quinolin-2-one
CFAMM00325882 CHEMBL89820 Bioactive 7-[4-oxo-4-(4-pyridin-2-ylpiperazin-1-yl)butoxy]-1,3-dihydroimidazo[4,5-b]quinolin-2-one
CFAMM00325896 CHEMBL92205 Bioactive SureCN10657130
CFAMM00325909 CHEMBL1203057 Bioactive 4-[(4-fluorophenyl)methyl]-N-[3-[(2-oxo-1,3-dihydroimidazo[4,5-b]quinolin-7-yl)oxy]propyl]piperazine-1-carboxamide;hydrochloride
CFAMM00325888 CHEMBL1203019 Bioactive 4-(cyclohexylmethyl)-N-[3-[(2-oxo-1,3-dihydroimidazo[4,5-b]quinolin-7-yl)oxy]propyl]piperazine-1-carboxamide;hydrochloride
CFAMM00325902 CHEMBL93730 Bioactive 7-[4-oxo-4-[4-(2-phenylethyl)piperazin-1-yl]butoxy]-1,3-dihydroimidazo[4,5-b]quinolin-2-one
CFAMM00325866 CHEMBL91388 Bioactive 7-[4-oxo-4-[4-[[4-(trifluoromethyl)phenyl]methyl]piperazin-1-yl]butoxy]-1,3-dihydroimidazo[4,5-b]quinolin-2-one
CFAMM00325881 CHEMBL92169 Bioactive SureCN7329232
CFAMM00325895 CHEMBL90876 Bioactive SureCN7329106
CFAMM00325908 CHEMBL327234 Bioactive SureCN7333083
CFAMM00325873 CHEMBL91010 Bioactive SureCN7334731
CFAMM00325887 CHEMBL330737 Bioactive 7-[4-[4-[(4-chlorophenyl)methyl]piperazin-1-yl]-4-oxobutoxy]-1,3-dihydroimidazo[4,5-b]quinolin-2-one
CFAMM00325901 CHEMBL329788 Bioactive 7-[4-oxo-4-[4-(2-propylpentyl)piperazin-1-yl]butoxy]-1,3-dihydroimidazo[4,5-b]quinolin-2-one
CFAMM00325880 CHEMBL314949 Bioactive SureCN7327642
CFAMM00325894 CHEMBL328711 Bioactive SureCN7325432
CFAMM00325872 CHEMBL90546 Bioactive SureCN7334081
CFAMM00325886 CHEMBL90176 Bioactive SureCN7327142
CFAMM00325913 CHEMBL90647 Bioactive 7-[4-[4-[bis(4-fluorophenyl)methyl]piperazin-1-yl]-4-oxobutoxy]-1,3-dihydroimidazo[4,5-b]quinolin-2-one
CFAMM00325864 CHEMBL329573 Bioactive 7-[4-[4-(oxan-2-ylmethyl)piperazin-1-yl]-4-oxobutoxy]-1,3-dihydroimidazo[4,5-b]quinolin-2-one
CFAMM00325879 CHEMBL313021 Bioactive SureCN7335008
CFAMM00325893 CHEMBL1203083 Bioactive 4-benzyl-N-[3-[(2-oxo-1,3-dihydroimidazo[4,5-b]quinolin-7-yl)oxy]propyl]piperazine-1-carboxamide;hydrochloride
CFAMM00325906 CHEMBL433183 Bioactive 7-[4-(4-benzylpiperazin-1-yl)-4-oxobutoxy]-1,3-dihydroimidazo[4,5-b]quinolin-2-one
CFAMM00325899 CHEMBL91503 Bioactive 7-[4-oxo-4-[4-[2-[2-(trifluoromethyl)phenyl]ethyl]piperazin-1-yl]butoxy]-1,3-dihydroimidazo[4,5-b]quinolin-2-one
CFAMM00325885 CHEMBL91249 Bioactive SureCN7326865
CFAMM00325912 CHEMBL329173 Bioactive 7-[4-[4-(2-cyclohexylethyl)piperazin-1-yl]-4-oxobutoxy]-1,3-dihydroimidazo[4,5-b]quinolin-2-one
CFAMM00325863 CHEMBL88787 Bioactive 7-[5-(4-benzylpiperazin-1-yl)-5-oxopentoxy]-1,3-dihydroimidazo[4,5-b]quinolin-2-one
CFAMM00325892 CHEMBL92165 Bioactive 7-[4-[4-(cyclopentylmethyl)piperazin-1-yl]-4-oxobutoxy]-1,3-dihydroimidazo[4,5-b]quinolin-2-one
CFAMM00325905 CHEMBL329412 Bioactive SureCN7323900
CFAMM00325884 CHEMBL91715 Bioactive SureCN7325332
CFAMM00325862 CHEMBL431085 Bioactive SureCN7332904
CFAMM00325877 CHEMBL330086 Bioactive SureCN7327236
CFAMM00325904 CHEMBL1203063 Bioactive 4-(2-ethylbutyl)-N-[3-[(2-oxo-1,3-dihydroimidazo[4,5-b]quinolin-7-yl)oxy]propyl]piperazine-1-carboxamide;hydrochloride
CFAMM00325868 CHEMBL327882 Bioactive 7-[4-[4-[(4-methoxyphenyl)methyl]piperazin-1-yl]-4-oxobutoxy]-1,3-dihydroimidazo[4,5-b]quinolin-2-one
CFAMM00325883 CHEMBL91088 Bioactive 7-[4-oxo-4-[4-[3-(trifluoromethyl)phenyl]piperazin-1-yl]butoxy]-1,3-dihydroimidazo[4,5-b]quinolin-2-one
CFAMM00325897 CHEMBL432057 Bioactive Bmy-43351
CFAMM00325910 CHEMBL90230 Bioactive SureCN7334616
CFAMM00325876 CHEMBL91014 Bioactive 7-[4-[4-(1,3-benzodioxol-5-ylmethyl)piperazin-1-yl]-4-oxobutoxy]-1,3-dihydroimidazo[4,5-b]quinolin-2-one
CFAMM00325889 CHEMBL90877 Bioactive 7-[4-[4-(cycloheptylmethyl)piperazin-1-yl]-4-oxobutoxy]-1,3-dihydroimidazo[4,5-b]quinolin-2-one

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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