CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM16350
Family Name Prostaglandin E synthase 2 inhibitor AGN-PC-075D2E family
No. of Seeds 1 No. of Other Members 0
Family Centroid CFAMM00437835 Functional Category Bioactive
Superfamily Oxysterols receptor LXR-beta and Oxysterols receptor LXR-alpha Binder Superfamily 7
Class Class 3040

Cousin Family NamesSeedsMembers
Cyclooxygenase Inhibitor Indomethacin Family 6 271
Arachidonate 5-lipoxygenase Inhibitor MK-591 Family 9 161
Prostaglandin E synthase Inhibitor L-655240 Family 3 46
Prostaglandin G/H synthase 2 Inhibitor L-761000 Family 8 44
Prostaglandin D2 receptor 2 ligand 2-[3-(4-chlorophenoxy)-5-fl... 3 3
Translocator protein inhibitor (4S)-N,N-diethyl-9-(2-fluoranyl... 9 10
Substance-P receptor ligand SureCN7796965 family 9 1
Cysteinyl leukotriene receptor 1 ligand 3-[5-[[3-[(E)-2-(7-chl... 1 1
Cysteinyl leukotriene receptor 1 ligand 3-[5-[[3-[(E)-2-(7-chl... 4 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00437835 CHEMBL369525 Bioactive AGN-PC-075D2E

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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