CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM16370
Family Name Serine/threonine-protein kinase mTOR and Peptidyl-prolyl cis-trans isomerase FKBP1A inhibitor CHEMBL371029 family
No. of Seeds 1 No. of Other Members 0
Family Centroid CFAMM00437884 Functional Category Bioactive
Superfamily Renin Inhibitor CP-80794 Superfamily
Class Class 1444

Cousin Family NamesSeedsMembers
ATP-sensitive inward rectifier potassium channel 10 Ligand Nat... 3 233
Bacterial outer membrane Inhibitor Polymyxin B Family 17 181
Renin Inhibitor CP-80794 Family 16 112
Cathepsin F and Cruzipain Inhibitor WRR-99 Family 13 131
Beta-secretase 1 Inhibitor MMI-175 Family 30 137
Plasmepsin-1 Inhibitor SC-5003 Family 93 173
Beta-secretase 1 Inhibitor Glu-leu-asp-leu-(choh-ch2)-ala-ala-... 15 11
Integrin alpha-V Inhibitor C[rgdf-(3s)-carboxymorpholine] Family 10 2
Caspase-4 and Cathepsin D Inhibitor Grassystatin A Family 24 6
Mu-type opioid receptor and Nociceptin receptor Ligand Nocicep... 35 5
Renin and Cathepsin D inhibitor (2S)-N-[(2S,3R,4S)-1-cyclohexy... 13 2
Renin inhibitor tert-butyl N-[1-[[(3S,6S,7R)-6-(cyclohexylmeth... 14 1
Neutrophil collagenase and Matrix metalloproteinase-9 inhibito... 6 1
Renin and Cathepsin D inhibitor (4S)-5-cyclohexyl-2,2-difluoro... 16 1
Peptidyl-prolyl cis-trans isomerase FKBP1A inhibitor CHEMBL266... 3 28
Peptidyl-prolyl cis-trans isomerase FKBP1A and Serine/threonin... 10 9
Renin and Cathepsin D inhibitor ethyl (4S)-5-cyclohexyl-2,2-di... 2 0
Peptidyl-prolyl cis-trans isomerase FKBP1A inhibitor CHEMBL437... 2 5


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00437884 CHEMBL371029 Bioactive CHEMBL371029

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

27425 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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