CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM16381
Family Name D(3) dopamine receptor and D(4) dopamine receptor ligand (7S)-7-(dipropylamino)-5,6,7,8-tetrahydroindolizine-3-carbonitrile family
No. of Seeds 1 No. of Other Members 2
Family Centroid CFAMM00437907 Functional Category Bioactive with Human Metabolite
Superfamily Tyrosinase Inhibitor 1-(2,5-dimethyl-1h-pyrrol-1-yl)thiourea Superfamily
Class Class 2150

Cousin Family NamesSeedsMembers
Nicotinic acetylcholine receptor Ligand Nicotine Family 14 686
Histamine H1 receptor Ligand Pheniramine Family 10 380
Histamine H1 receptor Ligand Triprolidine Family 19 316
Enoyl-[acyl-carrier-protein] reductase [NADH] Inhibitor Ethion... 5 68
G protein-activated inward rectifier potassium channel 4 Ligan... 3 48
Nicotinic acetylcholine receptor Ligand Epibatidine Family 36 19
5-hydroxytryptamine receptor 2A and 5-hydroxytryptamine recept... 6 17
Peptide deformylase, mitochondrial Inhibitor Hydroxy[3-(6-meth... 1 0
Neuronal acetylcholine receptor subunit alpha-4 and Neuronal a... 13 26
Inosine-5'-monophosphate dehydrogenase 2 Inhibitor 1-methyl-1h... 6 24
Acetylcholinesterase and Cholinesterase Inhibitor 1,9-bis(pyri... 8 38
Cytochrome P450 11B1, mitochondrial Inhibitor 2-methyl-1,2-di-... 8 15
S-adenosylmethionine decarboxylase proenzyme inhibitor 6-[(E)-... 2 6


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00437907 CHEMBL372020 Bioactive (7S)-7-(dipropylamino)-5,6,7,8-tetrahydroindolizine-3-carbonitrile

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

27526 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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