CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM16403
Family Name 72 kDa type IV collagenase and Disintegrin and metalloproteinase domain-containing protein 10 inhibitor (6S,7S)-N-hydroxy-6-(4-phenyl-3,6-dihydro-2H-pyridine-1-carbonyl)-5-azaspiro[2.5]octane-7-carboxamide family
No. of Seeds 1 No. of Other Members 13
Family Centroid CFAMM00228667 Functional Category Bioactive
Superfamily 72 kDa type IV collagenase and Disintegrin and metalloproteinase domain-containing protein 10 Binder Superfamily
Class Class 3289

Cousin Family NamesSeedsMembers
Vasopressin V1a receptor Ligand Felypressin Family 12 820
Alpha-1B adrenergic receptor Ligand Lisdexamfetamine Family 14 443
ATP-sensitive inward rectifier potassium channel 10 Ligand Nat... 3 233
Dipeptidyl peptidase 4 Inhibitor Denagliptin Family 24 151
Beta-secretase 1 Inhibitor N-(1-benzylpiperidin-4-yl)-4-sulfan... 7 62
72 kDa type IV collagenase and Matrix metalloproteinase-9 Inhi... 40 87
Disintegrin and metalloproteinase domain-containing protein 17... 8 7
Neuromedin-K receptor Ligand PD-157672 Family 9 37
Baculoviral IAP repeat-containing protein 3 and E3 ubiquitin-p... 44 28
Aminopeptidase N Inhibitor N1,2-dibenzyl-n3-hydroxymalonamide ... 5 23
Sodium channel protein type 1 subunit alpha and Sodium channel... 4 31
Aminopeptidase N Inhibitor 2-benzyl-n1-hydroxy-n3-(4-phenylbut... 5 3
Prolyl endopeptidase Inhibitor SUAM-1221 Family 42 47
Aminopeptidase N Inhibitor 2-cinnamamido-n4-hexyl-n1-hydroxysu... 24 8
72 kDa type IV collagenase and Matrilysin inhibitor (2S,3R)-N-... 1 0
Peptide deformylase inhibitor (2R)-N-[(2S)-1-(4-fluorophenyl)-... 4 0
Melanocortin receptor 4 and Melanocortin receptor 5 ligand (2S... 16 24
Muscarinic acetylcholine receptor M3 and Muscarinic acetylchol... 3 0
72 kDa type IV collagenase and Stromelysin-1 inhibitor (2R)-N-... 10 0
72 kDa type IV collagenase and Stromelysin-1 inhibitor methyl ... 6 2
Receptor tyrosine-protein kinase erbB-2 and Disintegrin and me... 3 4
Receptor tyrosine-protein kinase erbB-2 and Disintegrin and me... 1 0
Disintegrin and metalloproteinase domain-containing protein 10... 1 0


CFAM Mol ID

External ID

Functional Category

Molecule Name


Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

45910 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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