CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM16404
Family Name Neuronal acetylcholine receptor subunit alpha-4 and Neuronal acetylcholine receptor subunit beta-2 ligand SureCN650533 family
No. of Seeds 10 No. of Other Members 1
Family Centroid CFAMM00162114 Functional Category Bioactive
Superfamily Neuronal acetylcholine receptor subunit beta-2 and Neuronal acetylcholine receptor subunit alpha-4 Binder Superfamily 2
Class Class 1668

Cousin Family NamesSeedsMembers
Nicotinic acetylcholine receptor Ligand Nicotine Family 14 686
Histamine H1 receptor Ligand Pheniramine Family 10 380
Histamine H1 receptor Ligand Triprolidine Family 19 316
Enoyl-[acyl-carrier-protein] reductase [NADH] Inhibitor Ethion... 5 68
G protein-activated inward rectifier potassium channel 4 Ligan... 3 48
Metabotropic glutamate receptor 5 Ligand ADX-48621 Family 15 444
Neuronal acetylcholine receptor subunit alpha-4 and Neuronal a... 23 63
Amg 423 family 7 47
Nicotinic acetylcholine receptor Ligand Epibatidine Family 36 19
Ribonucleoside-diphosphate reductase large subunit Inhibitor T... 1 1
Carbonic anhydrase 2 Inhibitor Cyanamide Family 2 32
Cytochrome P450 11B1, mitochondrial and Aromatase Inhibitor 3-... 2 11
Cytochrome P450 11B1, mitochondrial and Aromatase Inhibitor 3-... 14 22
Neuronal acetylcholine receptor subunit alpha-4 and Neuronal a... 13 26
Transient receptor potential cation channel subfamily V member... 2 26
Protein kinase C theta type Inhibitor 4-(3h-indol-4-ylamino)-5... 2 2
Acetylcholinesterase and Cholinesterase Inhibitor 1,9-bis(pyri... 8 38
Prostaglandin G/H synthase 1 and Prostaglandin G/H synthase 2 ... 2 22
Carbonic anhydrase 1 and Carbonic anhydrase 2 Inhibitor 4-(met... 4 15
5-hydroxytryptamine receptor 2A and 5-hydroxytryptamine recept... 5 9
Macrophage migration inhibitory factor Inhibitor 1-(2-chloroph... 2 22
Cytochrome P450 11B1, mitochondrial Inhibitor 2-methyl-1,2-di-... 8 15
Amine oxidase [flavin-containing] A and Amine oxidase [flavin-... 4 6
Metabotropic glutamate receptor 5 Ligand 3-m-tolyl-1,5-naphthy... 6 10
Metabotropic glutamate receptor 5 Ligand 5-((6-methylpyridin-2... 14 22
Acetylcholinesterase and Cholinesterase Inhibitor Huprine-tacr... 62 27
D(2) dopamine receptor and D(3) dopamine receptor ligand AGN-P... 1 4
5-hydroxytryptamine receptor 1A and D(1A) dopamine receptor li... 2 3
Neuronal acetylcholine receptor subunit alpha-4 and Neuronal a... 4 5
5-hydroxytryptamine receptor 3A and 5-hydroxytryptamine recept... 7 4
Histamine H4 receptor ligand 4-[(3R)-3-(methylamino)pyrrolidin... 7 6
Neuronal acetylcholine receptor subunit alpha-4 and Neuronal a... 2 0
Neuronal acetylcholine receptor subunit alpha-4 and Neuronal a... 1 4
Neuronal acetylcholine receptor subunit alpha-4 and Neuronal a... 2 2
Neuronal acetylcholine receptor subunit alpha-4 and Neuronal a... 5 2
Neuronal acetylcholine receptor subunit beta-2 and Neuronal ac... 8 0
Neuronal acetylcholine receptor subunit alpha-4 and Neuronal a... 3 3
Neuronal acetylcholine receptor subunit alpha-4 and Neuronal a... 7 0
Neuronal acetylcholine receptor subunit alpha-4 and Neuronal a... 3 1
Ras-related protein Rab-9A and Niemann-Pick C1 protein inhibit... 1 2
Tyrosyl-DNA phosphodiesterase 1 and Inositol monophosphatase 1... 1 3
Potassium voltage-gated channel subfamily A member 5 and Inter... 2 0
Nitric oxide synthase, brain inhibitor SureCN1387416 family 2 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00438049 CHEMBL508645 Bioactive (1R,6S)-7-pyridin-3-yl-4,7-diazabicyclo[4.2.0]octane
CFAMM00438047 CHEMBL472243 Bioactive AGN-PC-077S0H
CFAMM00438046 CHEMBL376907 Bioactive (1S,6R)-4-(5,6-dibromopyridin-3-yl)-4,7-diazabicyclo[4.2.0]octane

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

27163 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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