CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM1641
Family Name Alpha-1D adrenergic receptor ligand 5-[(3-bromothiophen-2-yl)methyl]-1H-imidazole;hydrochloride family
No. of Seeds 8 No. of Other Members 0
Family Centroid CFAMM00325979 Functional Category Bioactive
Superfamily Alpha-1D adrenergic receptor and Methylated-DNA--protein-cysteine methyltransferase Binder Superfamily
Class Class 3420

Cousin Family NamesSeedsMembers
Alpha-2 adrenergic receptor Ligand Dexmedetomidine Family 32 639
Histamine H3 receptor and Histamine H4 receptor Ligand Clobenp... 31 38
Alpha-1A adrenergic receptor and Alpha-1B adrenergic receptor ... 4 22
Alpha-1A adrenergic receptor Ligand A-315456 Family 7 17
Indoleamine 2,3-dioxygenase 1 Inhibitor 3-(4h-imidazol-4-yl)be... 6 3
Cytochrome P450 2D6 and Cytochrome P450 3A4 Inhibitor 2-(2-(4-... 25 10
Histamine H3 receptor ligand SureCN7853275 family 2 5
Alpha-1D adrenergic receptor ligand (E)-but-2-enedioic acid;5-... 8 1
Alpha-1D adrenergic receptor ligand (E)-but-2-enedioic acid;5-... 1 0
Alpha-2A adrenergic receptor and Alpha-2C adrenergic receptor ... 1 0
Histamine H3 receptor and Histamine H4 receptor ligand AGN-PC-... 1 2


External ID

Functional Category

Molecule Name

CFAMM00325979 CHEMBL1203850 Bioactive 5-[(3-bromothiophen-2-yl)methyl]-1H-imidazole;hydrochloride
CFAMM00325978 CHEMBL1203852 Bioactive 5-[(4-bromothiophen-2-yl)methyl]-1H-imidazole;hydrochloride
CFAMM00325977 CHEMBL1237159 Bioactive 5-[1-(3-bromothiophen-2-yl)ethyl]-1H-imidazole;hydrochloride
CFAMM00325976 CHEMBL1203849 Bioactive 5-(thiophen-2-ylmethyl)-1H-imidazole;hydrochloride
CFAMM00325975 CHEMBL1203847 Bioactive 5-[(5-methylthiophen-2-yl)methyl]-1H-imidazole;hydrochloride
CFAMM00325981 CHEMBL1744280 Bioactive (E)-but-2-enedioic acid;5-[1-(3,4-dibromothiophen-2-yl)ethyl]-1H-imidazole
CFAMM00325974 CHEMBL355784 Bioactive 5-[1-(3-bromothiophen-2-yl)ethyl]-1H-imidazole
CFAMM00325980 CHEMBL1203855 Bioactive 5-[(3,4-dibromothiophen-2-yl)methyl]-1H-imidazole;hydrochloride

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

Last update by



54900 visits since 2014 .........


Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

All rights reserved.

Computer-aided Drug Design
about BIDD |  databases |  software |  teaching |  research |  links


Department of Computational Science | National University of Singapore | Blk S17, 3 Science Drive 2, Singapore 117543