CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM1642
Family Name NS5B protein inhibitor AC1NQMYG family
No. of Seeds 6 No. of Other Members 12
Family Centroid CFAMM00325999 Functional Category Bioactive with Natural Product
Superfamily NS5B protein and Retinoic acid receptor alpha Binder Superfamily
Class Class 3380

Cousin Family NamesSeedsMembers
5-hydroxytryptamine receptor 3A Ligand Dolasetron Family 12 171
Indoleamine 2,3-dioxygenase 1 Inhibitor L-tryptophan Family 8 328
Neuromedin-K receptor Ligand Talnetant Family 3 49
Dihydroorotate dehydrogenase Inhibitor Brequinar Family 9 122
Genomic RNA for RNA-dependent RNA polymerase gene (clone HCV-J... 4 42
Setipiprant family 5 118
Dihydroorotate dehydrogenase Inhibitor Cinchoninic Acid Family 1 21
Cannabinoid receptor 2 Ligand JWH-167 Family 25 168
Fatty acid-binding protein, adipocyte Inhibitor 2-(3-methyl-in... 5 9
Tyrosine-protein phosphatase non-receptor type 1 Ligand Cauler... 2 8
Lethal factor Inhibitor 3-(2,5-dimethyl-1h-pyrrol-1-yl)benzoic... 2 44
Fatty acid-binding protein, adipocyte Inhibitor 1-benzyl-2,3-d... 1 8
Cytosolic phospholipase A2 Inhibitor WAY-196025 Family 4 13
Kinesin-like protein KIF11 Inhibitor Methyl 7-tert-butyl-9h-ca... 2 9
Gamma-aminobutyric acid receptor subunit alpha-1 and Gamma-ami... 24 64
3-oxo-5-alpha-steroid 4-dehydrogenase 1 and 3-oxo-5-alpha-ster... 3 27
Prostaglandin E2 receptor EP4 subtype and Prostaglandin D2 rec... 8 17
Cathepsin K and Cathepsin S inhibitor dipeptidyl nitrile, 16f ... 3 18
5-hydroxytryptamine receptor 3E and 5-hydroxytryptamine recept... 10 4
Cannabinoid receptor 2 and Cannabinoid receptor 1 ligand [(4R,... 3 7
Prostaglandin G/H synthase 1 and Prostaglandin G/H synthase 2 ... 1 6
Retinoic acid receptor alpha and Retinoic acid receptor beta l... 1 2
Calpain-1 catalytic subunit and Cathepsin B inhibitor AGN-PC-0... 5 2
Cholecystokinin receptor type A and Gastrin/cholecystokinin ty... 4 53
Cannabinoid receptor 2 ligand [(4R,4aS,8aR)-4-hydroxy-4-phenyl... 2 41
cAMP-specific 3',5'-cyclic phosphodiesterase 4A and cAMP-speci... 4 4
Prostaglandin D2 receptor 2 and Prostaglandin D2 receptor liga... 20 37
Dipeptidyl peptidase 4 inhibitor AGN-PC-09QM95 family 1 1
Dipeptidyl peptidase 4 and Dipeptidyl peptidase 2 inhibitor AG... 1 0
Prothrombin and Trypsin-1 inhibitor 1-[2-(4-benzylpiperidin-1-... 2 2
Cannabinoid receptor 2 and Cannabinoid receptor 1 ligand [(4S,... 5 2
Prostaglandin D2 receptor 2 ligand SureCN2189431 family 7 1
NS5B protein inhibitor AGN-PC-00A17Z family 1 23
NS5B protein inhibitor AC1O5AET family 3 1
NS5B protein inhibitor AC1NQMYP family 5 0
5-hydroxytryptamine receptor 3A and 5-hydroxytryptamine recept... 9 6
Egl nine homolog 1 inhibitor 2-[5-methyl-6-[[1-oxo-2-(4-phenyl... 4 3
5-hydroxytryptamine receptor 4 ligand 4-[2-[4-[[(1-propan-2-yl... 1 1
Cannabinoid receptor 2 and Cannabinoid receptor 1 ligand SureC... 1 3
Gonadotropin-releasing hormone receptor ligand SureCN7905635 f... 2 2
Phospholipase A2, membrane associated inhibitor AGN-PC-075RBK ... 1 2
Gonadotropin-releasing hormone receptor ligand 4-[2-[[(2S)-2-[... 1 0
Adenosine receptor A2b and Adenosine receptor A1 ligand [4-(2,... 6 15
Serine/threonine-protein kinase Sgk1 inhibitor SureCN3774571 f... 2 18
Peroxisome proliferator-activated receptor gamma ligand AGN-PC... 4 4
Glutamate carboxypeptidase 2 inhibitor 1-[(3-carboxyphenyl)met... 4 11
Glutamate receptor 4 and Glutamate receptor 2 ligand SureCN437... 4 12
Thrombopoietin receptor ligand AGN-PC-077M9L family 2 4


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00325995 CHEMBL179673 Bioactive AC1NQMYV
CFAMM00325994 CHEMBL1203926 Bioactive 13-cyclohexyl-5-(2-piperidin-1-ylethyl)-6,7-dihydroindolo[1,2-d][1,4]benzodiazepine-10-carboxylic acid;dihydrochloride
CFAMM00326000 CHEMBL361156 Bioactive AC1NQMYS
CFAMM00325993 CHEMBL368647 Bioactive AC1NQMYD
CFAMM00325999 CHEMBL178126 Bioactive AC1NQMYG
CFAMM00325997 CHEMBL179532 Bioactive 3-CYCLOHEXYL-1-(2-MORPHOLIN-4-YL-2-OXOETHYL)-2-PHENYL-1H-INDOLE-6-CARBOXYLIC ACID

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

27619 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


All rights reserved.

   
 
 
Computer-aided Drug Design
about BIDD |  databases |  software |  teaching |  research |  links

 

Department of Computational Science | National University of Singapore | Blk S17, 3 Science Drive 2, Singapore 117543