CFam Chemical Families Database
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Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM1644
Family Name Muscarinic acetylcholine receptor M2 and Acetylcholinesterase ligand 2-[2-[[6-[2-(6-chloro-1,2,3,4-tetrahydroacridin-9-yl)hydrazinyl]-6-oxohexyl]carbamoyl]-4,5-bis[2-(triethylazaniumyl)ethoxy]phenoxy]ethyl-triethylazanium;tribromide family
No. of Seeds 4 No. of Other Members 24
Family Centroid CFAMM00326009 Functional Category Bioactive
Superfamily Acetylcholinesterase and Cholinesterase Binder Superfamily 2
Class Class 3421

Cousin Family NamesSeedsMembers
72 kDa type IV collagenase and Matrix metalloproteinase-9 Inhi... 37 265
von Willebrand factor Inhibitor Auryntricarboxylic Acid (ata) ... 12 81
5-hydroxytryptamine receptor 2C Ligand N-(6-phenoxypyridin-3-y... 9 69
Vasopressin V1a receptor and Vasopressin V2 receptor ligand (3... 4 41
B2 bradykinin receptor ligand (E)-N-[2-[2,4-dimethoxy-N-methyl... 3 2
Acetylcholinesterase and Muscarinic acetylcholine receptor M2 ... 2 7
Somatostatin receptor type 5 ligand AGN-PC-080TDB family 10 14
Histamine H3 receptor ligand AGN-PC-00BG7Z family 11 49
D(3) dopamine receptor and D(2) dopamine receptor ligand AGN-P... 4 6
B2 bradykinin receptor ligand 4-[(E)-3-[[2-[2,4-dichloro-3-[[4... 29 2
Cellular tumor antigen p53 and Microtubule-associated protein ... 1 4
B2 bradykinin receptor ligand SureCN6640854 family 7 4
Cellular tumor antigen p53 and Microtubule-associated protein ... 1 15
5-hydroxytryptamine receptor 1D and 5-hydroxytryptamine recept... 3 21
Butyrylcholinesterase and Acetylcholinesterase inhibitor AGN-P... 9 24
Histone deacetylase 3 and Histone deacetylase 9 inhibitor (3S,... 1 16
D(3) dopamine receptor ligand AGN-PC-075Z0O family 2 3
Histone deacetylase 6 and Histone deacetylase 1 inhibitor N-hy... 3 2
Cholinesterase and Acetylcholinesterase inhibitor 4-oxo-N-[9-(... 11 13
Cholinesterase and Acetylcholinesterase inhibitor 5-hydroxy-7-... 5 19
Acetylcholinesterase and Cholinesterase inhibitor N-[10-[(6-ch... 6 0
Histamine H3 receptor ligand 2-[4-(1-methylpyrrole-2-carbonyl)... 3 4
Cholinesterase and Acetylcholinesterase inhibitor tacrine deri... 10 0
Cathepsin K inhibitor N-[(2S)-4-methyl-1-[2-[4-(2-methylpropox... 4 0
Signal transducer and activator of transcription 1-alpha/beta ... 1 36


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00326030 CHEMBL1203984 Bioactive AGN-PC-088V3N
CFAMM00326009 CHEMBL555247 Bioactive 2-[2-[[6-[2-(6-chloro-1,2,3,4-tetrahydroacridin-9-yl)hydrazinyl]-6-oxohexyl]carbamoyl]-4,5-bis[2-(triethylazaniumyl)ethoxy]phenoxy]ethyl-triethylazanium;tribromide
CFAMM00326015 CHEMBL540132 Bioactive 2-[3-[[6-[2-(6-chloro-1,2,3,4-tetrahydroacridin-9-yl)hydrazinyl]-6-oxohexyl]carbamoyl]-5-[2-(triethylazaniumyl)ethoxy]phenoxy]ethyl-triethylazanium;dibromide
CFAMM00326032 CHEMBL1203986 Bioactive AGN-PC-046YIC

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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