CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM16443
Family Name Melanin-concentrating hormone receptor 1 and Potassium voltage-gated channel subfamily H member 2 ligand 6-chloro-4-[[1-(naphthalen-2-ylmethyl)piperidin-4-yl]amino]-1-(pyridin-2-ylmethyl)quinolin-2-one family
No. of Seeds 1 No. of Other Members 1
Family Centroid CFAMM00438158 Functional Category Bioactive
Superfamily ABC294640 Superfamily
Class Class 913

Cousin Family NamesSeedsMembers
5-hydroxytryptamine receptor 1B and 5-hydroxytryptamine recept... 14 2769
Histamine H1 receptor ligand tricyclic antidepressant Loratadi... 5 163
Glycogen phosphorylase, muscle form Inhibitor PSN357 Family 3 253
D(3) dopamine receptor Ligand SB-277011 Family 13 178
ABC294640 family 5 75
C-C chemokine receptor type 3 Ligand YM-344031 Family 19 106
Fibroblast growth factor receptor 2 Ligand Interferon Alfa (if... 14 162
5-hydroxytryptamine receptor 1A and 5-hydroxytryptamine recept... 4 93
Acetylcholinesterase and Cholinesterase Inhibitor Lipocrine Fa... 18 36
Mitogen-activated protein kinase 14 Inhibitor N-(4-fluorobenzy... 19 32
Sodium channel protein type 10 subunit alpha Ligand N-benzyl-5... 11 46
Vasopressin V2 receptor Ligand YM-35278 Family 33 38
Substance-P receptor ligand AGN-PC-01ZIXQ family 13 42
Prothrombin inhibitor SureCN7371121 family 13 3
RAC-alpha serine/threonine-protein kinase and Cyclin-dependent... 3 7
Vasopressin V2 receptor and Vasopressin V1a receptor ligand [2... 2 5
5-hydroxytryptamine receptor 1D and 5-hydroxytryptamine recept... 2 1
Serine/threonine-protein kinase pim-2 and Serine/threonine-pro... 6 9
Acetylcholinesterase inhibitor CHEMBL1651131 family 6 9
Substance-P receptor and Neuromedin-K receptor ligand SureCN88... 4 14
Histone deacetylase and Histone deacetylase 3 inhibitor (3S,6R... 2 2
Glycogen synthase kinase-3 beta inhibitor 7-(6-chloropyridin-2... 2 3
Acetylcholinesterase and Cholinesterase inhibitor AGN-PC-009GH... 8 10
Melanin-concentrating hormone receptor 1 and 5-hydroxytryptami... 1 1
Gonadotropin-releasing hormone receptor ligand 1-adamantyl-[2-... 3 1
Acetylcholinesterase inhibitor N-[6-[4-[(6-chloro-1,2,3,4-tetr... 9 0
C-C chemokine receptor type 1 ligand N-[(2R)-1-[4-(4-chlorophe... 2 1
cAMP-specific 3',5'-cyclic phosphodiesterase 4A and cAMP-speci... 2 2
Nociceptin receptor and Mu-type opioid receptor ligand N-[(1R,... 4 2
Reverse transcriptase/RNaseH inhibitor (4s)-6-chloro-4-cyclopr... 5 3


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00438158 CHEMBL377084 Bioactive 6-chloro-4-[[1-(naphthalen-2-ylmethyl)piperidin-4-yl]amino]-1-(pyridin-2-ylmethyl)quinolin-2-one

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

26194 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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