CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM16446
Family Name Tyrosine-protein phosphatase non-receptor type 1 ligand sodium;N-[(1S)-1-(6-chloro-1H-benzimidazol-2-yl)-2-[3-fluoro-4-(1,1,3-trioxo-4,5-dihydro-1,2-thiazol-2-id-5-yl)phenyl]ethyl]-3-(trifluoromethyl)benzenesulfonamide family
No. of Seeds 1 No. of Other Members 44
Family Centroid CFAMM00438194 Functional Category Bioactive
Superfamily Tyrosine-protein phosphatase non-receptor type 1 and Tyrosine-protein phosphatase non-receptor type 2 Binder Superfamily 4
Class Class 2756

Cousin Family NamesSeedsMembers
Prothrombin and Cationic trypsin inhibitor (2S)-N-[(2S)-1-(1H-... 4 15
Mitogen-activated protein kinase 14 inhibitor 6-[5-(2,4-difluo... 9 3
Orexin receptor type 2 and Orexin receptor type 1 ligand (2S)-... 2 2
5-hydroxytryptamine receptor 2B ligand SureCN1299053 family 1 1
Tyrosine-protein phosphatase non-receptor type 1 ligand sodium... 2 6
Tyrosine-protein phosphatase non-receptor type 1 ligand sodium... 1 0
Histone deacetylase 1 inhibitor (7S)-7-(5-naphthalen-2-yl-1H-i... 2 4
Tyrosine-protein phosphatase non-receptor type 1 and Tyrosine-... 1 15


External ID

Functional Category

Molecule Name

CFAMM00438194 CHEMBL377141 Bioactive sodium;N-[(1S)-1-(6-chloro-1H-benzimidazol-2-yl)-2-[3-fluoro-4-(1,1,3-trioxo-4,5-dihydro-1,2-thiazol-2-id-5-yl)phenyl]ethyl]-3-(trifluoromethyl)benzenesulfonamide

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

Last update by



82418 visits since 2014 .........


Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

All rights reserved.

Computer-aided Drug Design
about BIDD |  databases |  software |  teaching |  research |  links


Department of Computational Science | National University of Singapore | Blk S17, 3 Science Drive 2, Singapore 117543