CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM16454
Family Name Cathepsin K and Cathepsin L1 inhibitor dipeptidyl nitrile, 16c family
No. of Seeds 1 No. of Other Members 0
Family Centroid CFAMM00140160 Functional Category Bioactive
Superfamily Growth hormone secretagogue receptor type 1 Ligand TZP-101 Superfamily
Class Class 412

Cousin Family NamesSeedsMembers
Glycoprotein IIb/IIIa receptor Ligand Tirofiban Family 4 173
Growth hormone secretagogue receptor type 1 Ligand TZP-101 Family 28 263
Voltage-dependent L-type calcium channel Ligand PD173212 Family 24 104
Cathepsin F Inhibitor Benzoyl-tyrosine-alanine-methyl Ketone F... 34 55
Voltage-dependent N-type calcium channel subunit alpha-1B Liga... 2 2
Plasmepsin-1 and Plasmepsin-2 Inhibitor PS-777621 Family 11 13
Disintegrin and metalloproteinase domain-containing protein 17... 25 36
72 kDa type IV collagenase and Matrix metalloproteinase-9 Inhi... 9 12
Delta-type opioid receptor and Mu-type opioid receptor Ligand ... 152 36
Prothrombin and Tissue-type plasminogen activator inhibitor CH... 10 5
Pol polyprotein inhibitor MDL 74538 family 11 1
Cannabinoid receptor 1 and Cannabinoid receptor 2 ligand N-[(2... 10 12
Prostaglandin G/H synthase 1 and Prostaglandin G/H synthase 2 ... 3 191
Corticosteroid 11-beta-dehydrogenase isozyme 1 and Corticoster... 6 22
Motilin receptor ligand SureCN74051 family 1 0
Corticosteroid 11-beta-dehydrogenase isozyme 1 and Corticoster... 13 2
Corticosteroid 11-beta-dehydrogenase isozyme 1 and Corticoster... 2 1
Renin inhibitor (3S,6R)-6-(cyclohexylmethyl)-7-hydroxy-7-[[(2S... 1 0
Integrin beta-1 and Integrin alpha-4 inhibitor (2R)-3-[4-(2-me... 18 1
Plasmepsin-2 and Cathepsin D inhibitor N-[2-(1,3-benzodioxol-5... 4 0
Cathepsin S and Cathepsin L1 inhibitor benzyl N-[(2S)-1-oxo-1-... 2 2
Stromelysin-1 and Interstitial collagenase inhibitor (2R)-2-[4... 4 1
Neprilysin and Angiotensin-converting enzyme inhibitor (2S)-2-... 1 0
Scytalone dehydratase inhibitor 2-cyano-N-[(1S,2R)-1-(2-cyanop... 5 0
Growth hormone secretagogue receptor type 1 ligand N-benzyl-2-... 5 19
Metabotropic glutamate receptor 1 ligand methyl (2R)-2-[[(1aR,... 2 0


CFAM Mol ID

External ID

Functional Category

Molecule Name


Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

27432 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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