CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM16457
Family Name Microsomal triglyceride transfer protein large subunit inhibitor N-[4-[2-oxo-2-[[(1S)-2-oxo-1-phenyl-2-pyrrolidin-1-ylethyl]amino]ethyl]sulfanylphenyl]-2-[4-(trifluoromethyl)phenyl]benzamide family
No. of Seeds 2 No. of Other Members 0
Family Centroid CFAMM00438225 Functional Category Bioactive
Superfamily Cathepsin K and Cathepsin S Binder Superfamily 10
Class Class 1000

Cousin Family NamesSeedsMembers
Vasopressin V2 receptor Ligand FR161282 Family 17 83
Vasopressin V1a receptor and Vasopressin V2 receptor Ligand OP... 12 94
Farnesyltransferase beta subunit, putative and Protein farnesy... 24 82
Vasopressin V2 receptor and Vasopressin V1a receptor ligand 2-... 6 9
Microsomal triglyceride transfer protein large subunit inhibit... 8 1
Vasopressin V2 receptor and Vasopressin V1a receptor ligand AG... 5 1
Vasopressin V2 receptor and Vasopressin V1a receptor ligand 2-... 4 0


External ID

Functional Category

Molecule Name

CFAMM00438225 CHEMBL377824 Bioactive N-[4-[2-oxo-2-[[(1S)-2-oxo-1-phenyl-2-pyrrolidin-1-ylethyl]amino]ethyl]sulfanylphenyl]-2-[4-(trifluoromethyl)phenyl]benzamide
CFAMM00438224 CHEMBL379285 Bioactive N-[4-[2-[[(1S)-2-[benzyl(methyl)amino]-2-oxo-1-phenylethyl]amino]-2-oxoethyl]sulfanylphenyl]-2-[4-(trifluoromethyl)phenyl]benzamide

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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