CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM16463
Family Name Sodium-dependent serotonin transporter and Sodium-dependent noradrenaline transporter inhibitor SureCN5994139 family
No. of Seeds 2 No. of Other Members 11
Family Centroid CFAMM00438238 Functional Category Bioactive with Natural Product
Superfamily Substance-P receptor Ligand Ezlopitant Superfamily
Class Class 120

Cousin Family NamesSeedsMembers
Serotonin re-uptake Inhibitor Fluoxetine Family 18 682
Beta-2 adrenergic receptor Ligand Bambuterol Family 4 9
Alpha adrenergic receptor Ligand Phenoxybenzamine Family 4 63
Zucapsacin family 7 177
Serine/threonine-protein kinase PLK1 Inhibitor On 019190.na Fa... 16 138
Growth hormone secretagogue receptor type 1 Ligand TZP-101 Family 28 263
Substance-P receptor Ligand Ezlopitant Family 10 207
Acolbifene family 10 115
A disintegrin and metalloproteinase with thrombospondin motifs... 7 119
Potassium voltage-gated channel subfamily H member 2 and Sodiu... 33 83
C-C chemokine receptor type 5 Ligand E-913 Family 6 44
Extracellular calcium-sensing receptor Ligand Nps 568 Family 5 54
Voltage-dependent L-type calcium channel Ligand PD173212 Family 24 104
Histamine H3 receptor Ligand UCL-2138 Family 23 172
Alpha-1A adrenergic receptor and Alpha-1D adrenergic receptor ... 5 11
5-hydroxytryptamine receptor 1A and D(2) dopamine receptor Lig... 25 50
Plasmepsin-2 Inhibitor PS-662477 Family 7 55
Disintegrin and metalloproteinase domain-containing protein 17... 25 36
Adenosine receptor A3 and Muscarinic acetylcholine receptor M2... 4 31
Cannabinoid receptor 1 Ligand N-(3,5-dimethoxyphenethyl)oleami... 5 49
Cannabinoid receptor 1 Ligand N-(4-methoxyphenethyl)oleamide F... 10 36
Melanin-concentrating hormone receptor 1 Ligand N-(1-benzylpip... 9 57
Acetylcholinesterase and Cholinesterase Inhibitor Caproctamine... 7 17
Delta-type opioid receptor and Kappa-type opioid receptor Liga... 5 41
Alpha-2A adrenergic receptor and Alpha-2B adrenergic receptor ... 2 3
Tubulin beta chain Inhibitor Colchinol Family 3 109
5-hydroxytryptamine receptor 2A Ligand 1-(2,6-dimethoxy-4-meth... 14 3
5-hydroxytryptamine receptor 2C and 5-hydroxytryptamine recept... 1 0
Substance-P receptor ligand (2S,3S)-2-(3-chlorophenyl)-N-[(2,4... 1 0
3-hydroxyacyl-CoA dehydrogenase type-2 and Retinal dehydrogena... 1 15
Growth hormone secretagogue receptor type 1 ligand tert-butyl ... 5 4
Cathepsin K and Cathepsin S inhibitor (1R,2R)-N-[cyano-(2-meth... 1 0
Baculoviral IAP repeat-containing protein 3 and E3 ubiquitin-p... 7 1
Sigma non-opioid intracellular receptor 1 ligand (1S,4R,5R)-7-... 2 7
Substance-P receptor ligand (5S,10S)-5-(4-fluorophenyl)-10-(2-... 3 2
Integrin beta-3 and Integrin alpha-IIb inhibitor (3R)-3-(1,3-b... 4 2
Sigma non-opioid intracellular receptor 1 ligand (1R,5S)-9-[(4... 3 2
Acetyl-CoA carboxylase 2 and Acetyl-CoA carboxylase 1 inhibito... 2 3
Beta-lactamase and Histone-lysine N-methyltransferase 2A inhib... 1 7
7,8-dihydro-5H-[1,3]dioxolo[4,5-g]isoquinoline NP ZINC33345333... 21 3


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00438230 CHEMBL99260 Bioactive (2S)-2-amino-4-[(2,4-dimethoxyphenyl)methylamino]-1-piperidin-1-ylbutan-1-one
CFAMM00438238 CHEMBL378070 Bioactive SureCN5994139

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

41644 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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