CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM16467
Family Name Tyrosine-protein kinase Lck inhibitor SureCN374434 family
No. of Seeds 1 No. of Other Members 1
Family Centroid CFAMM00438253 Functional Category Bioactive
Superfamily Renin and Insulin-like growth factor 1 receptor Binder Superfamily
Class Class 1070

Cousin Family NamesSeedsMembers
Serine/threonine-protein kinase PLK1 Inhibitor Bi 6727 Family 15 81
Receptor tyrosine-protein kinase erbB-2 Inhibitor CP-724714 Fa... 4 180
Smoothened homolog Inhibitor LDE225 Family 3 76
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subun... 11 10
Proto-oncogene tyrosine-protein kinase Src Inhibitor PD166285 ... 6 70
5-hydroxytryptamine receptor 1A Ligand P-MPPI Family 33 81
Angiopoietin-1 receptor and Tyrosine-protein kinase Lck Inhibi... 4 32
Peptidyl-prolyl cis-trans isomerase A Inhibitor 3-[3-(3-benzyl... 3 34
Platelet-derived growth factor receptor alpha and Fibroblast g... 3 47
C-X-C chemokine receptor type 3 Ligand AMG-487 Family 28 73
Tyrosine-protein kinase JAK3 and Tyrosine-protein kinase JAK2 ... 1 11
Mitogen-activated protein kinase 14 inhibitor N-(4-aminobutyl)... 1 28
Cyclin-dependent kinase 4 and G1/S-specific cyclin-D1 inhibito... 1 0
Inositol monophosphatase 1 inhibitor CHEMBL1588383 family 1 6
Melanocortin receptor 4 ligand AGN-PC-076AML family 3 24
Prostaglandin D2 receptor ligand 1-[3-[2-methoxy-6-[2-(4-metho... 6 16
Serine/threonine-protein kinase PLK1 inhibitor AGN-PC-0A9RFQ f... 2 1
Dihydrofolate reductase inhibitor 3-(2,4-diamino-6-methylquina... 2 1
Cathepsin S and Cathepsin L1 inhibitor arylaminoethyl amide, 1... 1 0
Rho-associated protein kinase 1 and cAMP-dependent protein kin... 1 11
Receptor tyrosine-protein kinase erbB-2 ligand SureCN4461871 f... 2 2
Tyrosine-protein kinase ABL1 and Breakpoint cluster region pro... 8 5
Vasopressin V1a receptor and Vasopressin V2 receptor ligand AG... 2 2
Alpha-1A adrenergic receptor and Alpha-1D adrenergic receptor ... 6 0
Tyrosine-protein kinase Lck inhibitor N-(5-tert-butyl-1,2-oxaz... 1 0
Tyrosine-protein kinase Lck and Mitogen-activated protein kina... 2 0
Insulin-like growth factor 1 receptor ligand SureCN311483 family 3 0
Aurora kinase A and Aurora kinase B inhibitor AGN-PC-071H3F fa... 3 0
Acyl-CoA desaturase inhibitor SureCN1182546 family 2 5
Receptor tyrosine-protein kinase erbB-2 ligand AGN-PC-0766EI f... 1 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00438253 CHEMBL378410 Bioactive SureCN374434

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

44593 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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