CFam Chemical Families Database
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Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM1647
Family Name Beta-2 adrenergic receptor and Beta-1 adrenergic receptor ligand phenyl N-[4-[2-[[(2S)-2-hydroxy-3-phenoxypropyl]amino]ethyl]phenyl]carbamate;hydrochloride family
No. of Seeds 3 No. of Other Members 6
Family Centroid CFAMM00232008 Functional Category Bioactive
Superfamily Beta-1 adrenergic receptor and Beta-2 adrenergic receptor Binder Superfamily 4
Class Class 3302

Cousin Family NamesSeedsMembers
Beta adrenergic receptor ligand naphthol derivative Propranolo... 11 218
Beta-2 adrenergic receptor Ligand Formoterol Family 16 63
Beta-1 adrenergic receptor Ligand Metoprolol Family 29 90
Beta-1 adrenergic receptor Ligand Acebutolol Family 2 27
Potassium voltage-gated channel subfamily H member 2 Ligand Do... 5 30
Beta-1 adrenergic receptor Ligand Practolol Family 2 82
Histamine H1 receptor Ligand Tranilast Family 5 125
5-hydroxytryptamine receptor 1A Ligand (s)-way 100135 Family 94 975
Beta-3 adrenergic receptor Ligand Cgp 12177 Family 3 8
CGMP-inhibited 3',5'-cyclic phosphodiesterase Inhibitor Cilost... 6 202
Potassium voltage-gated channel subfamily H member 2 and Sodiu... 33 83
Histamine H3 receptor Ligand UCL1972 Family 3 23
Leukotriene A-4 hydrolase Inhibitor N5-[4-(phenylmethoxy)pheny... 7 49
Leukotriene A-4 hydrolase Inhibitor N-benzyl-4-[(2r)-pyrrolidi... 6 40
5-hydroxytryptamine receptor 1A and D(2) dopamine receptor Lig... 25 50
Beta-1 adrenergic receptor and Beta-2 adrenergic receptor Liga... 40 90
Oxytocin receptor and Vasopressin V1a receptor Ligand L-371257... 8 92
Substance-K receptor Ligand MEN-14933 Family 13 154
Alpha-1A adrenergic receptor Ligand Upidosin Family 8 46
Alpha-1A adrenergic receptor Ligand Naftopidil Family 15 119
Alpha-1A adrenergic receptor and D(2) dopamine receptor Ligand... 5 49
5-hydroxytryptamine receptor 1A and Sodium-dependent dopamine ... 9 79
Renin Inhibitor Ro-66-1168 Family 10 30
Galanin receptor type 1 and Galanin receptor type 2 Ligand Gal... 55 132
Reverse transcriptase Inhibitor 10-propyl-10h-dibenzo[b,f][1,4... 9 60
Alpha-2A adrenergic receptor and Alpha-2B adrenergic receptor ... 2 3
Tyrosinase Inhibitor 1-(4-(benzyloxy)phenyl)-3-hydroxyurea Family 9 23
Beta-3 adrenergic receptor and Beta-1 adrenergic receptor liga... 1 0
Beta-1 adrenergic receptor ligand 1-[2-[[(2S)-3-(2-cyanophenox... 10 4
Beta-2 adrenergic receptor and Beta-1 adrenergic receptor liga... 6 2
Beta-1 adrenergic receptor ligand 4-[2-[[(2S)-3-(2-cyano-5-flu... 3 2
Alpha-2B adrenergic receptor and Alpha-2C adrenergic receptor ... 2 0
Beta-3 adrenergic receptor and Beta-2 adrenergic receptor liga... 5 3
Histamine H3 receptor and Potassium voltage-gated channel subf... 3 4
D(2) dopamine receptor and 5-hydroxytryptamine receptor 1A lig... 2 3
Multidrug resistance protein 1 inhibitor 1-[2-[(2R)-3-[4-(2,3-... 2 41
Sodium-dependent serotonin transporter inhibitor SureCN3890472... 2 0
Beta-3 adrenergic receptor and Beta-1 adrenergic receptor liga... 1 1
Beta-3 adrenergic receptor and Beta-1 adrenergic receptor liga... 6 1
Androgen receptor ligand AGN-PC-00BRQF family 2 2
C-C chemokine receptor type 1 ligand N-[2-[(2S)-3-(5-chlorospi... 4 0
Beta-1 adrenergic receptor and Beta-2 adrenergic receptor liga... 4 8
Beta-1 adrenergic receptor and Beta-2 adrenergic receptor liga... 3 0
Histamine H3 receptor and Sodium-dependent serotonin transport... 2 1
Capsid scaffolding protein inhibitor AC1MHP1L family 3 6
Neuropeptide Y receptor type 5 ligand 3-[4-(4-fluorophenoxy)ph... 4 0
Beta-3 adrenergic receptor ligand 4-[4-[2-[[(2R)-2-(4-aminophe... 3 0
Beta-1 adrenergic receptor and Beta-3 adrenergic receptor liga... 1 1
Amyloid beta A4 protein inhibitor 2-(fluoranylmethyl)-3-[4-[(E... 1 3
Beta-1 adrenergic receptor and Beta-3 adrenergic receptor liga... 2 0
Sigma non-opioid intracellular receptor 1 and 5-hydroxytryptam... 2 8
Glutamate receptor ionotropic, NMDA 1 ligand N-[4-[(2S)-3-[2-(... 2 6
Sodium channel protein type 1 subunit alpha and Sodium channel... 3 0
cGMP-inhibited 3',5'-cyclic phosphodiesterase B and cGMP-inhib... 1 1
Cytochrome P450 2D6 and Sodium channel protein type 1 subunit ... 1 1


CFAM Mol ID

External ID

Functional Category

Molecule Name


Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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