CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM16471
Family Name Cyclooxygenase 2 and Prostaglandin G/H synthase 1 inhibitor 2-[5-[4-(furan-2-yl)-3-methylphenyl]-3-(trifluoromethyl)pyrazol-1-yl]-5-methylsulfonylpyridine family
No. of Seeds 2 No. of Other Members 10
Family Centroid CFAMM00438309 Functional Category Bioactive
Superfamily Prelamin-A/C and Cyclooxygenase 2 Binder Superfamily
Class Class 2484

Cousin Family NamesSeedsMembers
Glycogen synthase kinase-3 beta and Glycogen synthase kinase-3... 4 4
Cyclooxygenase 2 and Prostaglandin G/H synthase 1 inhibitor Su... 7 6
Cyclooxygenase 2 and Prostaglandin G/H synthase 1 inhibitor AG... 1 2


External ID

Functional Category

Molecule Name

CFAMM00438309 CHEMBL378649 Bioactive 2-[5-[4-(furan-2-yl)-3-methylphenyl]-3-(trifluoromethyl)pyrazol-1-yl]-5-methylsulfonylpyridine
CFAMM00438305 CHEMBL380148 Bioactive SureCN6963221

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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