CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM1648
Family Name Beta-1 adrenergic receptor ligand 4-[2-[[(2S)-3-(2-cyano-5-fluorophenoxy)-2-hydroxypropyl]amino]ethylcarbamoylamino]benzoic acid family
No. of Seeds 3 No. of Other Members 2
Family Centroid CFAMM00326053 Functional Category Bioactive
Superfamily Beta-1 adrenergic receptor and Beta-2 adrenergic receptor Binder Superfamily 4
Class Class 3302

Cousin Family NamesSeedsMembers
Beta-1 adrenergic receptor Ligand Acebutolol Family 2 27
Beta-1 adrenergic receptor and Beta-2 adrenergic receptor Liga... 40 90
Reverse transcriptase Inhibitor 10-propyl-10h-dibenzo[b,f][1,4... 9 60
Tyrosinase Inhibitor 1-(4-(benzyloxy)phenyl)-3-hydroxyurea Family 9 23
Beta-1 adrenergic receptor ligand 1-[2-[[(2S)-3-(2-cyanophenox... 10 4
Beta-2 adrenergic receptor and Beta-1 adrenergic receptor liga... 6 2
Beta-2 adrenergic receptor and Beta-1 adrenergic receptor liga... 3 6
Alpha-2B adrenergic receptor and Alpha-2C adrenergic receptor ... 2 0
Multidrug resistance protein 1 inhibitor 1-[2-[(2R)-3-[4-(2,3-... 2 41
Beta-3 adrenergic receptor and Beta-1 adrenergic receptor liga... 6 1
Bifunctional epoxide hydrolase 2 inhibitor dimethyl 5-[4-[(4-m... 1 0
Muscarinic acetylcholine receptor M3 and Muscarinic acetylchol... 12 13
Bifunctional epoxide hydrolase 2 inhibitor 3-[4-[[4-(trifluoro... 5 22
Beta-1 adrenergic receptor and Beta-2 adrenergic receptor liga... 3 0
Capsid scaffolding protein inhibitor AC1MHP1L family 3 6
Neuropeptide Y receptor type 5 ligand 3-[4-(4-fluorophenoxy)ph... 4 0
Beta-3 adrenergic receptor ligand 4-[4-[2-[[(2R)-2-(4-aminophe... 3 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00326053 CHEMBL2011221 Bioactive 4-[2-[[(2S)-3-(2-cyano-5-fluorophenoxy)-2-hydroxypropyl]amino]ethylcarbamoylamino]benzoic acid
CFAMM00326051 CHEMBL2011222 Bioactive 4-[2-[[(2S)-3-(2-cyanophenoxy)-2-hydroxypropyl]amino]ethylcarbamoylamino]-2-fluorobenzoic acid

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

38799 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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