CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM16506
Family Name Proteinase-activated receptor 1 ligand (3R,3aS,4S,4aR,8aS,9aR)-4-[(E)-2-(6-hydroxyquinolin-2-yl)ethenyl]-3-methyl-3a,4,4a,5,6,7,8,8a,9,9a-decahydro-3H-benzo[f][2]benzofuran-1-one family
No. of Seeds 1 No. of Other Members 11
Family Centroid CFAMM00438421 Functional Category Bioactive
Superfamily Proteinase-activated receptor 1 and Vascular endothelial growth factor receptor 2 Binder Superfamily
Class Class 2321

Cousin Family NamesSeedsMembers
Phospholipase A2 Inhibitor Quinacrine Family 13 95
Arachidonate 5-lipoxygenase-activating protein Inhibitor DG031... 3 206
Proteinase-activated receptor 1 Ligand SCH-530348 Family 20 215
Metabotropic glutamate receptor 5 Ligand 3-methoxy-5-(2-methyl... 7 27
Leukotriene B4 receptor 1 and Leukotriene B4 receptor 2 ligand... 2 18
Peroxisome proliferator-activated receptor gamma ligand AGN-PC... 5 12
Proteinase-activated receptor 1 ligand (3R,3aR,4S,5R,6S,7aS)-5... 2 3
3-hydroxy-3-methylglutaryl-coenzyme A reductase inhibitor Sure... 2 6
Arachidonate 5-lipoxygenase-activating protein inhibitor 2-[[4... 7 4
3-hydroxy-3-methylglutaryl-coenzyme A reductase inhibitor (4R,... 2 0
Dipeptidyl peptidase 4 inhibitor 2-[3-(aminomethyl)-4-(4-fluor... 3 0
Proteinase-activated receptor 1 ligand (3R,3aS,4S,4aR,8aS,9aR)... 1 1
Proteinase-activated receptor 1 ligand 2-[2-[(E)-2-[(3R,3aS,4S... 1 2


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00438421 CHEMBL381265 Bioactive (3R,3aS,4S,4aR,8aS,9aR)-4-[(E)-2-(6-hydroxyquinolin-2-yl)ethenyl]-3-methyl-3a,4,4a,5,6,7,8,8a,9,9a-decahydro-3H-benzo[f][2]benzofuran-1-one

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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