CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM16525
Family Name Poly [ADP-ribose] polymerase 1 inhibitor 1-(4-methoxyphenyl)-3-methyl-N-[3-[(4-oxo-3H-phthalazin-1-yl)methyl]phenyl]pyrazole-4-carboxamide family
No. of Seeds 1 No. of Other Members 0
Family Centroid CFAMM00438469 Functional Category Bioactive
Superfamily Prelamin-A/C and Menin Binder Superfamily 8
Class Class 842

Cousin Family NamesSeedsMembers
Mitogen-activated protein kinase 12 Inhibitor ARRY-797 Family 13 41
5-hydroxytryptamine receptor 2C Ligand N-(6-phenoxypyridin-3-y... 9 69
Gamma-aminobutyric acid receptor subunit alpha-1 and Gamma-ami... 2 31
5-hydroxytryptamine receptor 2A and Potassium voltage-gated ch... 5 0
D(2) dopamine receptor and D(4) dopamine receptor ligand N-[3-... 6 22
Serine/threonine-protein kinase RIO2 and Serine/threonine-prot... 19 10
D(2) dopamine receptor and D(3) dopamine receptor ligand N-[3-... 7 3
Smoothened homolog and Mitogen-activated protein kinase 14 inh... 3 0
cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10... 1 0
Serine/threonine-protein kinase PLK4 inhibitor (3E)-5-methoxy-... 4 0
cAMP-specific 3',5'-cyclic phosphodiesterase 4B inhibitor Sure... 13 9
Adenosine receptor A3 and Adenosine receptor A1 ligand 2-(3-me... 2 10
Adenosine receptor A3 and Adenosine receptor A1 ligand N-[2-(4... 3 2
Tyrosine-protein kinase Lck inhibitor AGN-PC-07R5ZB family 4 3
Diacylglycerol O-acyltransferase 1 inhibitor AGN-PC-07ZCRO family 1 2
Glucagon receptor ligand AGN-PC-0DAGZC family 3 12
Cyclin-dependent kinase 2 inhibitor N-[(4-chlorophenyl)carbamo... 3 0
Dual specificity mitogen-activated protein kinase kinase 1 inh... 2 5


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00438469 CHEMBL382950 Bioactive 1-(4-methoxyphenyl)-3-methyl-N-[3-[(4-oxo-3H-phthalazin-1-yl)methyl]phenyl]pyrazole-4-carboxamide

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

45918 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


All rights reserved.

   
 
 
Computer-aided Drug Design
about BIDD |  databases |  software |  teaching |  research |  links

 

Department of Computational Science | National University of Singapore | Blk S17, 3 Science Drive 2, Singapore 117543