CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM16533
Family Name Sodium-dependent serotonin transporter and Sodium-dependent dopamine transporter inhibitor (1S,4S)-4-(3,4-dichlorophenyl)-N-methyl-7-(1,2,4-triazol-1-yl)-1,2,3,4-tetrahydronaphthalen-1-amine family
No. of Seeds 1 No. of Other Members 0
Family Centroid CFAMM00438490 Functional Category Bioactive
Superfamily Sodium-dependent dopamine transporter and Sodium-dependent serotonin transporter Binder Superfamily 14
Class Class 2257

Cousin Family NamesSeedsMembers
Corticotropin-releasing factor receptor 1 Ligand Dmp-695/696 F... 11 20
Gamma-aminobutyric acid receptor subunit alpha-1 and Gamma-ami... 3 63
Prelamin-A/C inhibitor CHEMBL1472945 family 1 32
Sigma non-opioid intracellular receptor 1 ligand 1-(3,4-dichlo... 2 19
P2X purinoceptor 7 inhibitor 2-(2,3-dichlorophenyl)-N-[(2-meth... 4 17
P2X purinoceptor 7 inhibitor N-benzyl-1-(2,3-dichlorophenyl)te... 19 0
Potassium voltage-gated channel subfamily A member 5 ligand (7... 5 18
Potassium voltage-gated channel subfamily A member 5 ligand 7-... 5 0


External ID

Functional Category

Molecule Name

CFAMM00438490 CHEMBL383427 Bioactive (1S,4S)-4-(3,4-dichlorophenyl)-N-methyl-7-(1,2,4-triazol-1-yl)-1,2,3,4-tetrahydronaphthalen-1-amine

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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