CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM16536
Family Name Melanin-concentrating hormone receptor 1 and Cytochrome P450 2D6 ligand N-[(3S)-1-[(3R)-3-[(4,4-dimethylcyclohexyl)amino]pyrrolidine-1-carbonyl]pyrrolidin-3-yl]-5-(4-methoxy-2-methylphenyl)-N-methylthiophene-2-carboxamide family
No. of Seeds 4 No. of Other Members 0
Family Centroid CFAMM00438498 Functional Category Bioactive
Superfamily Urotensin-2 receptor and Kappa-type opioid receptor Binder Superfamily
Class Class 511

Cousin Family NamesSeedsMembers
Urotensin-2 receptor Ligand SB-328872 Family 5 24
Delta-type opioid receptor and Kappa-type opioid receptor Liga... 5 14
Vasopressin V1a receptor and Vasopressin V2 receptor ligand [4... 2 3
Delta-type opioid receptor and Mu-type opioid receptor ligand ... 3 10
Mu-type opioid receptor ligand AGN-PC-075GCP family 2 8
Melanin-concentrating hormone receptor 1 ligand (3S)-3-[[5-(4-... 4 5
Fatty-acid amide hydrolase 1 inhibitor [3-(3-carbamoyl-5-methy... 1 1
D(3) dopamine receptor and D(2) dopamine receptor ligand N-[4-... 2 4
Delta-type opioid receptor and Mu-type opioid receptor ligand ... 2 9


External ID

Functional Category

Molecule Name

CFAMM00438496 CHEMBL384622 Bioactive 5-(2,3-dihydro-1,4-benzodioxin-6-yl)-N-[(3S)-1-[(3R)-3-[(4,4-dimethylcyclohexyl)amino]pyrrolidine-1-carbonyl]pyrrolidin-3-yl]-N-methylthiophene-2-carboxamide
CFAMM00438499 CHEMBL386454 Bioactive N-[(3S)-1-[(3R)-3-[(4,4-dimethylcyclohexyl)amino]pyrrolidine-1-carbonyl]pyrrolidin-3-yl]-5-(4-methoxyphenyl)-N-methylthiophene-2-carboxamide
CFAMM00438498 CHEMBL383933 Bioactive N-[(3S)-1-[(3R)-3-[(4,4-dimethylcyclohexyl)amino]pyrrolidine-1-carbonyl]pyrrolidin-3-yl]-5-(4-methoxy-2-methylphenyl)-N-methylthiophene-2-carboxamide
CFAMM00438497 CHEMBL387013 Bioactive N-[(3S)-1-[(3R)-3-(3-cyclohexylpropylamino)pyrrolidine-1-carbonyl]pyrrolidin-3-yl]-5-(4-methoxy-2-methylphenyl)-N-methylthiophene-2-carboxamide

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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