CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM16540
Family Name Tyrosine-protein kinase Lck inhibitor AGN-PC-03HL8Q family
No. of Seeds 4 No. of Other Members 0
Family Centroid CFAMM00438535 Functional Category Bioactive
Superfamily Tyrosine-protein kinase Lck and Glucokinase Binder Superfamily
Class Class 1600

Cousin Family NamesSeedsMembers
Abelson tyrosine-protein kinase 2 inhibitor thiazole derivativ... 19 50
Mast/stem cell growth factor receptor Kit and Abelson tyrosine... 6 537
DNA primase Inhibitor Bay 57-1293 Family 1 2
Metabotropic glutamate receptor 5 Ligand N-[4-(3-pyridylethyny... 2 10
Cyclin-dependent kinase 5 Inhibitor 1-phenyl-3-(2-(pyridin-4-y... 3 53
Mitogen-activated protein kinase 11 and Mitogen-activated prot... 10 31
Poly [ADP-ribose] polymerase 1 Inhibitor N-(4-phenylthiazol-2-... 6 150
Cyclin-T1 and Cyclin-dependent kinase 9 inhibitor 2-[3-(4-acet... 4 12
Neuropeptide Y receptor type 5 ligand 2-phenyl-1-[(1R,5S)-6-[[... 9 11
Proto-oncogene tyrosine-protein kinase Src and Tyrosine-protei... 1 1
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subun... 2 8
Thyroid hormone receptor beta and Ferritin light chain ligand ... 3 10
Cellular tumor antigen p53 inhibitor CHEMBL1395891 family 1 6
Inhibitor of nuclear factor kappa-B kinase subunit beta and In... 7 21
Mitogen-activated protein kinase 14 inhibitor N-[4-[2-ETHYL-4-... 4 5
Protein kinase C zeta type and Inhibitor of nuclear factor kap... 1 6
Serine/threonine-protein kinase Chk1 and Cyclin-dependent kina... 15 8
Serine/threonine-protein kinase Chk1 and Cyclin-dependent kina... 2 8
Orexin receptor type 2 and Orexin receptor type 1 ligand (2-me... 3 1
D(3) dopamine receptor and D(2) dopamine receptor ligand [4-[2... 6 5
Metabotropic glutamate receptor 5 ligand 5-methyl-N-(4-methyl-... 1 2
Vascular endothelial growth factor receptor 2 ligand N-(1,3-Th... 4 4
NAD-dependent protein deacetylase sirtuin-2 and NAD-dependent ... 8 12
High affinity nerve growth factor receptor and Hepatocyte grow... 6 8
Tyrosine-protein kinase Lck inhibitor AGN-PC-074MSE family 18 2
Tyrosine-protein kinase Lck inhibitor AGN-PC-074MPV family 4 0
Mitogen-activated protein kinase 14 inhibitor 303163-37-3 family 1 2
Tyrosine-protein kinase Lck inhibitor AGN-PC-03HLHQ family 2 0
Proto-oncogene tyrosine-protein kinase LCK and Tyrosine-protei... 3 9
Methionine aminopeptidase and Methionine aminopeptidase 1 inhi... 3 7
Tyrosine-protein kinase ITK/TSK inhibitor AGN-PC-03LEDF family 3 4
Glucokinase inhibitor AGN-PC-078XNA family 2 9


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00438538 CHEMBL384307 Bioactive AGN-PC-03HL80
CFAMM00438537 CHEMBL385172 Bioactive AGN-PC-03HL6U
CFAMM00438536 CHEMBL386745 Bioactive AGN-PC-03HLG8
CFAMM00438535 CHEMBL386371 Bioactive AGN-PC-03HL8Q

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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