CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM16582
Family Name 72 kDa type IV collagenase inhibitor AGN-PC-03EJ2S family
No. of Seeds 8 No. of Other Members 5
Family Centroid CFAMM00438688 Functional Category Bioactive
Superfamily Histamine H3 receptor and Dipeptidyl peptidase 4 Binder Superfamily
Class Class 412

Cousin Family NamesSeedsMembers
Disintegrin and metalloproteinase domain-containing protein 17... 25 36
5-hydroxytryptamine receptor 1A and 5-hydroxytryptamine recept... 6 12
Matrix metalloproteinase-9 inhibitor N-[1-(4,4-dimethyl-2,5-di... 3 3
Dipeptidyl peptidase 4 inhibitor 2-cyanopyrrolidine 21e family 6 7
72 kDa type IV collagenase and Matrix metalloproteinase-9 inhi... 2 0


External ID

Functional Category

Molecule Name

CFAMM00438689 CHEMBL416421 Bioactive AGN-PC-03ES0N
CFAMM00438682 CHEMBL75437 Bioactive AGN-PC-074ISA
CFAMM00438688 CHEMBL38868 Bioactive AGN-PC-03EJ2S
CFAMM00438680 CHEMBL41408 Bioactive AGN-PC-03ERZ3
CFAMM00438685 CHEMBL43411 Bioactive AGN-PC-00F01C
CFAMM00438690 CHEMBL40143 Bioactive ABT-770
CFAMM00438683 CHEMBL41102 Bioactive N-[1-[4-(4-cyanophenyl)phenoxy]-3-(4,4-dimethyl-2,5-dioxoimidazolidin-1-yl)propan-2-yl]-N-hydroxyformamide

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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