CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM16583
Family Name Neprilysin inhibitor (2S)-4-methoxy-2-[[1-[[(1R,2S)-2-(4-methoxyphenyl)cyclopropyl]carbamoyl]cyclopentyl]methyl]butanoic acid family
No. of Seeds 1 No. of Other Members 0
Family Centroid CFAMM00438692 Functional Category Bioactive
Superfamily Neprilysin Inhibitor Candoxatril Superfamily
Class Class 579

Cousin Family NamesSeedsMembers
Glycoprotein IIb/IIIa receptor Ligand Tirofiban Family 4 173
Zucapsacin family 7 177
Thymopentin family 20 133
Growth hormone secretagogue receptor type 1 Ligand TZP-101 Family 28 263
A disintegrin and metalloproteinase with thrombospondin motifs... 7 119
Vasopeptidase Inhibitor Sampatrilat Family 25 9
Voltage-dependent L-type calcium channel Ligand PD173212 Family 24 104
Cathepsin F Inhibitor Benzoyl-tyrosine-alanine-methyl Ketone F... 34 55
Disintegrin and metalloproteinase domain-containing protein 17... 25 36
72 kDa type IV collagenase and Matrix metalloproteinase-9 Inhi... 9 12
Proto-oncogene tyrosine-protein kinase Src Inhibitor Ac-cys-il... 36 12
72 kDa type IV collagenase and Matrix metalloproteinase-9 inhi... 3 4
Neprilysin and Angiotensin-converting enzyme inhibitor AGN-PC-... 3 7
Glutamate receptor ionotropic, kainate 2 ligand (2S,3S,4S)-4-[... 4 10
Serine palmitoyltransferase 1 and Serine palmitoyltransferase ... 2 1
Calpain-1 catalytic subunit and Cathepsin B inhibitor AGN-PC-0... 6 1
Neprilysin inhibitor SureCN389939 family 5 6
Angiotensin-converting enzyme and Neprilysin inhibitor (2S,5R)... 15 3
Angiotensin-converting enzyme 2 and Neprilysin inhibitor (2S)-... 6 1
Integrin beta-1 and Integrin alpha-4 inhibitor (2S)-3-[4-(2-me... 4 0
Neprilysin and Angiotensin-converting enzyme inhibitor (2S)-2-... 1 0
Sodium channel protein type 9 subunit alpha ligand (1R,2R)-N-b... 5 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00438692 CHEMBL389061 Bioactive (2S)-4-methoxy-2-[[1-[[(1R,2S)-2-(4-methoxyphenyl)cyclopropyl]carbamoyl]cyclopentyl]methyl]butanoic acid

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

26413 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


All rights reserved.

   
 
 
Computer-aided Drug Design
about BIDD |  databases |  software |  teaching |  research |  links

 

Department of Computational Science | National University of Singapore | Blk S17, 3 Science Drive 2, Singapore 117543