CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM16592
Family Name Serine/threonine-protein kinase Chk1 inhibitor SureCN4849127 family
No. of Seeds 4 No. of Other Members 1
Family Centroid CFAMM00438709 Functional Category Bioactive
Superfamily Serine/threonine-protein kinase Chk1 and Cyclin-dependent kinase 1 Binder Superfamily
Class Class 1583

Cousin Family NamesSeedsMembers
Histone deacetylase 2 Inhibitor N-(4-amino-3'-methoxybiphenyl-... 3 49
Serine/threonine-protein kinase Chk1 inhibitor 9-(4-amino-3-me... 3 7
Serine/threonine-protein kinase Chk1 inhibitor 2-[9-(4-amino-3... 5 2
Serine/threonine-protein kinase Chk1 inhibitor 2,3-dimethoxy-9... 15 3
Vascular endothelial growth factor receptor 2 ligand CHEMBL197... 1 1
Serine/threonine-protein kinase Chk1 inhibitor SureCN4856064 f... 1 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00438711 CHEMBL564952 Bioactive 2-[9-(3-methoxy-4-nitrophenyl)-6-oxo-5,11-dihydrobenzo[b][1,4]benzodiazepin-3-yl]-2-methylpropanoic acid
CFAMM00438710 CHEMBL562875 Bioactive Chk1_80
CFAMM00438709 CHEMBL389816 Bioactive SureCN4849127
CFAMM00438708 CHEMBL558077 Bioactive 3-(1-hydroxy-2-methylpropan-2-yl)-9-(3-methoxy-4-nitrophenyl)-5,11-dihydrobenzo[b][1,4]benzodiazepin-6-one

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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