CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM16607
Family Name 3-hydroxy-3-methylglutaryl-coenzyme A reductase inhibitor (3R,5R)-7-[5-[benzyl(methyl)carbamoyl]-3-(4-fluorophenyl)-4-phenyl-1-propan-2-ylpyrrol-2-yl]-3,5-dihydroxyheptanoic acid family
No. of Seeds 3 No. of Other Members 3
Family Centroid CFAMM00438779 Functional Category Bioactive
Superfamily 3-hydroxy-3-methylglutaryl-coenzyme A reductase Inhibitor Atorvastatin Superfamily
Class Class 327

Cousin Family NamesSeedsMembers
3-hydroxy-3-methylglutaryl-coenzyme A reductase Inhibitor Ator... 3 24
3-hydroxy-3-methylglutaryl-coenzyme A reductase Inhibitor Fluv... 6 53
3-hydroxy-3-methylglutaryl-coenzyme A reductase Inhibitor PF-3... 6 1


External ID

Functional Category

Molecule Name

CFAMM00438779 CHEMBL391002 Bioactive (3R,5R)-7-[5-[benzyl(methyl)carbamoyl]-3-(4-fluorophenyl)-4-phenyl-1-propan-2-ylpyrrol-2-yl]-3,5-dihydroxyheptanoic acid
CFAMM00438784 CHEMBL471745 Bioactive (3R,5R)-7-[3-(4-fluorophenyl)-4-methyl-5-(phenylcarbamoyl)-1H-pyrrol-2-yl]-3,5-dihydroxyheptanoic acid
CFAMM00438783 CHEMBL455524 Bioactive (3R,5R)-7-[3-(4-fluorophenyl)-5-[(4-methoxycarbonylphenyl)carbamoyl]-1-methyl-4-phenylpyrrol-2-yl]-3,5-dihydroxyheptanoic acid

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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Computer-aided Drug Design
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