CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM1661
Family Name 5-hydroxytryptamine receptor 1A and Alpha-1B adrenergic receptor ligand propyl 2-[4-[4-(1,3-dioxo-5,6,7,7a-tetrahydropyrrolo[1,2-c]imidazol-2-yl)butyl]piperazin-1-yl]benzoate;hydrochloride family
No. of Seeds 3 No. of Other Members 14
Family Centroid CFAMM00326124 Functional Category Bioactive with Natural Product
Superfamily Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform Inhibitor AZD6482 Superfamily
Class Class 257

Cousin Family NamesSeedsMembers
Integrin alpha-4 Inhibitor R1295 Family 18 59
Alpha-1A adrenergic receptor and Alpha-1D adrenergic receptor ... 2 2
Integrin beta-1 and Integrin alpha-4 inhibitor 4-[[1-[2-[4-[(2... 2 8
Type-2 angiotensin II receptor ligand (2S)-4-(dipentylcarbamoy... 1 0
Aldose reductase inhibitor ethyl 3-methyl-2,2',5'-trioxospiro[... 1 2
Putative NP ZINC04043929 Family 4 1


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00326127 CHEMBL62017 Bioactive propyl 2-[4-[4-(1,3-dioxo-5,6,7,7a-tetrahydropyrrolo[1,2-c]imidazol-2-yl)butyl]piperazin-1-yl]benzoate
CFAMM00326124 CHEMBL1204239 Bioactive propyl 2-[4-[4-(1,3-dioxo-5,6,7,7a-tetrahydropyrrolo[1,2-c]imidazol-2-yl)butyl]piperazin-1-yl]benzoate;hydrochloride
CFAMM00326128 CHEMBL56878 Bioactive ethyl 2-[4-[2-(7,9-dioxo-8-azaspiro[4.5]decan-8-yl)ethyl]piperazin-1-yl]benzoate

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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