CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM1666
Family Name Gonadotropin-releasing hormone receptor and Gonadotropin-releasing hormone receptor ligand 4-[2-[(2S)-azetidin-2-yl]ethoxy]-7-chloro-2-oxo-N-pyrimidin-4-yl-3-(3,4,5-trimethylphenyl)-1H-quinoline-6-carboxamide family
No. of Seeds 2 No. of Other Members 2
Family Centroid CFAMM00326157 Functional Category Bioactive
Superfamily Gonadotropin-releasing hormone receptor and Tyrosine-protein kinase Lck Binder Superfamily
Class Class 6

Cousin Family NamesSeedsMembers
Gonadotropin-releasing hormone receptor ligand 7-chloro-3-(3,5... 28 19
Somatostatin receptor type 2 ligand SureCN4325675 family 3 1
Somatostatin receptor type 2 ligand SureCN4317006 family 10 1
Gonadotropin-releasing hormone receptor ligand 7-chloro-2-oxo-... 11 0
Gonadotropin-releasing hormone receptor ligand 4-[2-[(2S)-azet... 1 0
Gonadotropin-releasing hormone receptor ligand 7-chloro-3-(3,5... 2 1


External ID

Functional Category

Molecule Name

CFAMM00326154 CHEMBL1766106 Bioactive 7-chloro-3-(3,5-dimethylphenyl)-4-(2-piperidin-2-ylethoxy)-6-pyrimidin-4-yl-1H-quinolin-2-one
CFAMM00326157 CHEMBL120432 Bioactive 4-[2-[(2S)-azetidin-2-yl]ethoxy]-7-chloro-2-oxo-N-pyrimidin-4-yl-3-(3,4,5-trimethylphenyl)-1H-quinoline-6-carboxamide

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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Computer-aided Drug Design
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