CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM16660
Family Name C-X-C chemokine receptor type 3 ligand N-[(1R)-1-[4-oxo-3-(4-prop-1-ynylphenyl)quinazolin-2-yl]ethyl]-N-(pyridin-3-ylmethyl)-2-[4-(trifluoromethyl)phenyl]acetamide family
No. of Seeds 2 No. of Other Members 1
Family Centroid CFAMM00438983 Functional Category Bioactive
Superfamily Glutamate receptor 1 Ligand Piriqualone Superfamily
Class Class 840

Cousin Family NamesSeedsMembers
Reverse transcriptase Inhibitor Nevirapine Family 23 640
SUR2-type K(ATP) channel Ligand Nicorandil Family 5 85
Mitogen-activated protein kinase 14 Inhibitor Losmapimod Family 5 154
Mast/stem cell growth factor receptor Kit and Vascular endothe... 4 47
D(3) dopamine receptor Ligand SB-277011 Family 13 178
Substance-P receptor Ligand TAK-637 Family 18 63
Histone deacetylase 6 Inhibitor ACY-1215 Family 10 230
C-C chemokine receptor type 3 Ligand YM-344031 Family 19 106
XL-888 family 16 85
Histone deacetylase 1 and Histone deacetylase 2 Inhibitor N-(4... 4 21
Adenosine receptor A1 and Adenosine receptor A3 Ligand VUF-850... 28 47
Transient receptor potential cation channel subfamily V member... 6 23
Cannabinoid receptor 1 Ligand N-phenyl-5,6-dip-tolylpyrazine-2... 11 26
Nitric oxide synthase, inducible and Nitric oxide synthase, br... 4 6
Bifunctional epoxide hydrolase 2 Inhibitor N-(3,3-diphenyl-pro... 6 14
Mitogen-activated protein kinase 14 Inhibitor N-(4-fluorobenzy... 19 32
Glutamate receptor 1 Ligand Piriqualone Family 8 67
Vasopressin V2 receptor Ligand YM-35278 Family 33 38
Dipeptidyl peptidase 4 inhibitor (1S,3S,5S)-2-[(2S)-2-amino-2-... 3 5
Tyrosine-protein kinase JAK2 and Tyrosine-protein kinase JAK1 ... 2 4
Nicotinamide phosphoribosyltransferase inhibitor 4-[(7-chloro-... 6 4
Coagulation factor X inhibitor AGN-PC-075AY8 family 28 21
5-hydroxytryptamine receptor 1A and 5-hydroxytryptamine recept... 9 19
Acetylcholinesterase inhibitor CHEMBL1651131 family 6 9
C-X-C chemokine receptor type 3 ligand N-[(1R)-1-[3-(4-cyanoph... 6 6
C-X-C chemokine receptor type 3 ligand N-[(1R)-1-[3-(4-chlorop... 4 0
5-hydroxytryptamine receptor 1A and 5-hydroxytryptamine recept... 7 1
Mitogen-activated protein kinase 14 and Mitogen-activated prot... 1 1
Aurora kinase A and Aurora kinase B inhibitor 4-fluoro-N-[4-[(... 6 1
Dipeptidyl peptidase 4 inhibitor 2-[(3R)-3-aminopiperidin-1-yl... 3 4
Motilin receptor ligand SureCN2768052 family 3 0
Nicotinamide phosphoribosyltransferase inhibitor 4-[[7-bromo-3... 1 0
Phospholipase D1 and Phospholipase D2 inhibitor SureCN10311349... 2 14
Glutamate receptor 1 and Glutamate receptor 2 ligand cp-465022... 1 6
Coagulation factor X inhibitor AGN-PC-078Y0T family 11 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00438983 CHEMBL395745 Bioactive N-[(1R)-1-[4-oxo-3-(4-prop-1-ynylphenyl)quinazolin-2-yl]ethyl]-N-(pyridin-3-ylmethyl)-2-[4-(trifluoromethyl)phenyl]acetamide
CFAMM00438984 CHEMBL395746 Bioactive N-[(1R)-1-[3-(4-nitrophenyl)-4-oxoquinazolin-2-yl]ethyl]-N-(pyridin-3-ylmethyl)-2-[4-(trifluoromethyl)phenyl]acetamide

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

27674 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


All rights reserved.

   
 
 
Computer-aided Drug Design
about BIDD |  databases |  software |  teaching |  research |  links

 

Department of Computational Science | National University of Singapore | Blk S17, 3 Science Drive 2, Singapore 117543