CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM1668
Family Name Sodium-dependent noradrenaline transporter inhibitor 3-[1-(2-fluorophenyl)-2,2-dioxo-3,4-dihydro-2$l^{6},1-benzothiazin-3-yl]-N-methylpropan-1-amine;hydrochloride family
No. of Seeds 2 No. of Other Members 13
Family Centroid CFAMM00326203 Functional Category Bioactive with Natural Product
Superfamily Huntingtin and Glucocorticoid receptor Binder Superfamily
Class Class 3425

Cousin Family NamesSeedsMembers
Noradrenergic re-uptake inhibitor Dibenzazepine Imipramine Family 8 178
Cannabinoid receptor 1 Ligand AVE1625 Family 2 19
Progesterone receptor Ligand 2,2,4-trimethyl-6-phenyl-1,2-dihy... 5 82
5-hydroxytryptamine receptor 1A and 5-hydroxytryptamine recept... 9 67
5-hydroxytryptamine receptor 1A and 5-hydroxytryptamine recept... 5 18
D(3) dopamine receptor and D(2) dopamine receptor ligand N-[4-... 8 10
Nociceptin receptor and Mu-type opioid receptor ligand AGN-PC-... 2 5
Cannabinoid receptor 2 and Cannabinoid receptor 1 ligand N-[[4... 7 11
Growth hormone secretagogue receptor type 1 ligand SureCN47963... 3 3
Beta-3 adrenergic receptor and Beta-2 adrenergic receptor liga... 3 0
5-hydroxytryptamine receptor 6 ligand AGN-PC-077LIW family 1 0
Glucocorticoid receptor ligand AGN-PC-01X8EB family 1 2


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00326203 CHEMBL1204411 Bioactive 3-[1-(2-fluorophenyl)-2,2-dioxo-3,4-dihydro-2$l^{6},1-benzothiazin-3-yl]-N-methylpropan-1-amine;hydrochloride
CFAMM00326200 CHEMBL1204412 Bioactive 3-[1-(2,6-difluorophenyl)-2,2-dioxo-3,4-dihydro-2$l^{6},1-benzothiazin-3-yl]-N-methylpropan-1-amine;hydrochloride

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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