CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM16683
Family Name Coagulation factor X inhibitor SureCN8290907 family
No. of Seeds 2 No. of Other Members 2
Family Centroid CFAMM00439053 Functional Category Bioactive
Superfamily P2X purinoceptor 7 and Beta-lactamase Binder Superfamily
Class Class 4

Cousin Family NamesSeedsMembers
Prothrombin Inhibitor Dabigatran Family 7 182
Type-2 angiotensin II receptor Ligand L-158282 Family 24 58
5-hydroxytryptamine receptor 1F and 5-hydroxytryptamine recept... 2 13
Aurora kinase B and Aurora kinase A inhibitor AGN-PC-07ZBLC fa... 3 8
Insulin receptor and Tyrosine-protein kinase Lck ligand AGN-PC... 1 1
Receptor tyrosine-protein kinase erbB-2 ligand AGN-PC-07ZDR2 f... 7 33
Coagulation factor X inhibitor 3-[2-(5-chlorothiophen-2-yl)-3H... 1 10
Coagulation factor X inhibitor SureCN3862475 family 5 2
Coagulation factor X inhibitor SureCN1678771 family 1 0
Cell division cycle 7-related protein kinase and Cyclin-depend... 2 9
Serine/threonine-protein kinase Chk1 inhibitor 2-(1-methylindo... 3 4
Peroxisome proliferator-activated receptor gamma ligand 1-[(4-... 7 29
Prelamin-A/C and Niemann-Pick C1 protein inhibitor CHEMBL13592... 1 16
Thyroid hormone receptor beta and Ferritin light chain ligand ... 3 10
5-hydroxytryptamine receptor 4 ligand 6-chloro-N-[[1-(2-methyl... 10 19
cGMP-dependent 3',5'-cyclic phosphodiesterase and cAMP and cAM... 8 13
Coagulation factor X and Prothrombin inhibitor 2-carboxyindole... 2 8
Inhibitor of nuclear factor kappa-B kinase subunit beta and In... 7 21
Histamine H3 receptor and Potassium voltage-gated channel subf... 7 1
Coagulation factor X inhibitor SureCN8289965 family 4 5
Protein kinase C zeta type and Inhibitor of nuclear factor kap... 1 6
Cell division cycle 7-related protein kinase and Protein DBF4 ... 2 1
Glycogen synthase kinase-3 beta inhibitor N-[2-[4-(ethylsulfon... 2 2
Coagulation factor X inhibitor 3-chloro-N-[(1S,2S)-2-[[4-(2-ox... 22 3
Melanocortin receptor 4 ligand AGN-PC-076AMO family 17 8
Melanocortin receptor 4 ligand AGN-PC-076ANF family 1 0
Protein farnesyltransferase/geranylgeranyltransferase type-1 s... 5 4
Corticotropin-releasing factor receptor 1 and Corticotropin-re... 2 1
Cyclin-dependent kinase 2 and Potassium voltage-gated channel ... 12 7
Adenosine receptor A1 and Adenosine receptor A2a ligand AGN-PC... 1 0
RAC-alpha serine/threonine-protein kinase and RAC-gamma serine... 20 7
Tyrosine-protein kinase ITK/TSK inhibitor SureCN6632543 family 1 2


External ID

Functional Category

Molecule Name

CFAMM00439049 CHEMBL400226 Bioactive 5-chloro-N-[(1R,2S)-2-[[4-[2-[(dimethylamino)methyl]imidazol-1-yl]benzoyl]amino]cyclohexyl]thiophene-2-carboxamide
CFAMM00439053 CHEMBL398998 Bioactive SureCN8290907

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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