CFam Chemical Families Database
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Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM167
Family Name Pol polyprotein inhibitor tert-butyl N-[(2S,3S,5R)-3-hydroxy-6-[[(2R)-2-hydroxy-2,3-dihydro-1H-inden-1-yl]amino]-5-[(4-hydroxyphenyl)methyl]-6-oxo-1-phenylhexan-2-yl]carbamate family
No. of Seeds 11 No. of Other Members 8
Family Centroid CFAMM00308312 Functional Category Bioactive
Superfamily Pol polyprotein and Matrix metalloproteinase-9 Binder Superfamily
Class Class 3076

Cousin Family NamesSeedsMembers
Voltage-dependent L-type calcium channel Ligand PD173212 Family 24 104
Cathepsin F Inhibitor Benzoyl-tyrosine-alanine-methyl Ketone F... 34 55
Beta-secretase 1 Inhibitor MMI-175 Family 30 137
Plasmepsin-1 Inhibitor SC-5003 Family 93 173
Plasmepsin-2 Inhibitor KNI-10232 Family 8 36
Pol polyprotein inhibitor tert-butyl N-[(2S,3S,5R)-3-hydroxy-6... 40 29
Pol polyprotein inhibitor 180968-31-4 family 8 13
Pol polyprotein inhibitor AC1L9R8S family 5 4
Pol polyprotein inhibitor (2S)-4-benzyl-1-[(2S,4R)-4-benzyl-2-... 10 4
72 kDa type IV collagenase and Matrix metalloproteinase-9 inhi... 3 4
Pol polyprotein inhibitor MK-944a family 6 1
Calpain-1 catalytic subunit and Cathepsin B inhibitor AGN-PC-0... 6 1
Pol polyprotein inhibitor (2R)-2-benzyl-5-[(3S,5R)-3-benzyl-5-... 11 5
Pol polyprotein inhibitor 3-[[(3S,5R)-5-benzyl-1-[(2S,4R)-4-be... 4 0
Pol polyprotein inhibitor AC1LADII family 12 1
Pol polyprotein inhibitor SureCN3530080 family 3 8
Pol polyprotein inhibitor tert-butyl N-[(2S,3S,5R)-5-benzyl-3-... 3 0
Pol polyprotein inhibitor L-689,502 family 17 2
A disintegrin and metalloproteinase with thrombospondin motifs... 2 2
Pol polyprotein inhibitor SDZ PRI 053 family 8 1
72 kDa type IV collagenase and Matrix metalloproteinase-9 inhi... 4 4
Pol polyprotein inhibitor tert-butyl N-[(2S,3S,5S)-3-hydroxy-5... 4 12
Pol polyprotein inhibitor AC1NS2O6 family 3 0
Pol polyprotein inhibitor AC1L9R8I family 1 0
Pol polyprotein inhibitor AC1L9R8M family 4 1
Pol polyprotein inhibitor (2S)-1-[(2S,4R)-4-benzyl-2-hydroxy-5... 2 0
Pol polyprotein inhibitor (2R)-5-[(3S,5R)-3,5-dibenzyl-2-oxopy... 3 0
Pol polyprotein inhibitor (2R,4S)-2-benzyl-5-[2-(tert-butylsul... 1 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00308323 CHEMBL298316 Bioactive AC1L9R8W
CFAMM00308329 CHEMBL297189 Bioactive AC1L9R8V
CFAMM00308328 CHEMBL295470 Bioactive tert-butyl N-[(2S,3S,5R)-3-hydroxy-6-[[(2R)-2-hydroxy-2,3-dihydro-1H-inden-1-yl]amino]-1-(4-hydroxyphenyl)-5-[(4-hydroxyphenyl)methyl]-6-oxohexan-2-yl]carbamate
CFAMM00308321 CHEMBL103400 Bioactive tert-butyl N-[(2S,3S,5R)-5-benzyl-6-[[(1R,2S,3R)-2,3-dihydroxy-2,3-dihydro-1H-inden-1-yl]amino]-3-hydroxy-6-oxo-1-phenylhexan-2-yl]carbamate
CFAMM00308314 CHEMBL430875 Bioactive tert-butyl N-[(2S,3S,5R)-5-[[(1R,2S,3R)-2,3-dihydroxy-2,3-dihydro-1H-inden-1-yl]carbamoyl]-3-hydroxy-1,8-diphenyloctan-2-yl]carbamate
CFAMM00308320 CHEMBL297045 Bioactive tert-butyl N-[(2S,3S,5R)-5-benzyl-3-hydroxy-6-[[(2R)-2-hydroxy-2,3-dihydro-1H-inden-1-yl]amino]-1-(4-hydroxyphenyl)-6-oxohexan-2-yl]carbamate
CFAMM00308326 CHEMBL295530 Bioactive AC1NS2JU
CFAMM00308312 CHEMBL290987 Bioactive tert-butyl N-[(2S,3S,5R)-3-hydroxy-6-[[(2R)-2-hydroxy-2,3-dihydro-1H-inden-1-yl]amino]-5-[(4-hydroxyphenyl)methyl]-6-oxo-1-phenylhexan-2-yl]carbamate
CFAMM00308318 CHEMBL318531 Bioactive tert-butyl N-[(2S,3S,5R)-3-hydroxy-6-[[(1R,2R)-2-hydroxy-2,3-dihydro-1H-inden-1-yl]amino]-5-[(4-hydroxyphenyl)methyl]-6-oxo-1-phenylhexan-2-yl]carbamate
CFAMM00308324 CHEMBL419923 Bioactive N-t-Butyloxycarbonyl-5-amino-1,6-diphenyl-4-hydroxy-2-(2,3-dihydroxyindanacetylamino)-hexane
CFAMM00308317 CHEMBL322984 Bioactive tert-butyl N-[(2S,3S,5R)-5-[[(1S,2S,3R)-2,3-dihydroxy-2,3-dihydro-1H-inden-1-yl]carbamoyl]-3-hydroxy-1,8-diphenyloctan-2-yl]carbamate

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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