CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM16700
Family Name Vascular endothelial growth factor receptor 2 and Vascular endothelial growth factor receptor 1 ligand 2-methyl-4-(pyridin-4-ylmethylamino)-N-[4-(trifluoromethoxy)phenyl]pyrazole-3-carboxamide family
No. of Seeds 2 No. of Other Members 3
Family Centroid CFAMM00147304 Functional Category Bioactive
Superfamily Bifunctional epoxide hydrolase 2 Inhibitor N-benzyl-6-(3,3,3-trifluoropropoxy)nicotinamide Superfamily
Class Class 1163

Cousin Family NamesSeedsMembers
Mast/stem cell growth factor receptor Kit and Vascular endothe... 1 4
Coagulation factor X Inhibitor Apixaban Family 34 52
DCC-2036 family 2 5
Bifunctional epoxide hydrolase 2 Inhibitor N-benzyl-6-(3,3,3-t... 21 62
Gamma-aminobutyric acid receptor subunit alpha-1 and Gamma-ami... 2 31
Serine/threonine-protein kinase PLK1 and Serine/threonine-prot... 14 42
D(2) dopamine receptor and D(4) dopamine receptor ligand N-[3-... 6 22
Alpha-1A adrenergic receptor and Alpha-1D adrenergic receptor ... 4 11
Coagulation factor X and Prothrombin inhibitor 6-[4-[2-[[(3R)-... 15 2
Gamma-aminobutyric acid receptor subunit gamma-2 and Gamma-ami... 3 2
D(2) dopamine receptor and D(3) dopamine receptor ligand N-[3-... 7 3
Smoothened homolog and Mitogen-activated protein kinase 14 inh... 3 0
Coagulation factor X and Prothrombin inhibitor 1-(4-methoxyphe... 8 0
Coagulation factor X inhibitor SureCN6785555 family 7 0
Orexin receptor type 2 and Orexin receptor type 1 ligand [(2R,... 4 0
Alpha-1A adrenergic receptor and Alpha-1D adrenergic receptor ... 6 0
Adenosine receptor A3 and Adenosine receptor A1 ligand 2-(3-me... 2 10
Adenosine receptor A3 and Adenosine receptor A1 ligand N-[2-(4... 3 2
Coagulation factor X inhibitor AGN-PC-046RMQ family 1 0
Coagulation factor X inhibitor AGN-PC-077MYE family 16 0
Coagulation factor X inhibitor SureCN5644036 family 30 0
Coagulation factor X inhibitor AGN-PC-077MVW family 5 0
Alpha-1A adrenergic receptor and Alpha-1D adrenergic receptor ... 2 1
Diacylglycerol O-acyltransferase 1 inhibitor AGN-PC-07ZCRO family 1 2
Glucagon receptor ligand AGN-PC-0DAGZC family 3 12
Vascular endothelial growth factor receptor 2 and Vascular end... 1 1


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00439113 CHEMBL574132 Bioactive 2-(4-methoxyphenyl)-5-methyl-4H-pyrazolo[4,3-d]pyrimidin-7-one

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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