CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM1674
Family Name Cannabinoid receptor 2 and Cannabinoid receptor 1 ligand [(4R,4aS,8aR)-4-hydroxy-4-phenyl-2,3,4a,5,6,7,8,8a-octahydroquinolin-1-yl]-quinolin-2-ylmethanone family
No. of Seeds 3 No. of Other Members 7
Family Centroid CFAMM00326303 Functional Category Bioactive
Superfamily Cannabinoid receptor 2 and Cannabinoid receptor 1 Binder Superfamily 9
Class Class 3108

Cousin Family NamesSeedsMembers
5-hydroxytryptamine receptor 1B and 5-hydroxytryptamine recept... 14 2769
HIV protease Inhibitor Saquinavir Family 64 428
Neuromedin-K receptor Ligand SB222200 Family 17 235
Dihydroorotate dehydrogenase Inhibitor Brequinar Family 9 122
D(3) dopamine receptor Ligand SB-277011 Family 13 178
Substance-P receptor Ligand TAK-637 Family 18 63
Genomic RNA for RNA-dependent RNA polymerase gene (clone HCV-J... 4 42
Setipiprant family 5 118
CP-18770 family 6 27
Fibroblast growth factor receptor 2 Ligand Interferon Alfa (if... 14 162
Cholecystokinin receptor type A Ligand VL-0395 Family 12 117
Lethal factor Inhibitor 3-(2,5-dimethyl-1h-pyrrol-1-yl)benzoic... 2 44
Microsomal triglyceride transfer protein large subunit Inhibit... 5 9
Mitogen-activated protein kinase 14 Inhibitor N-(4-fluorobenzy... 19 32
Acetylcholinesterase and Cholinesterase Inhibitor 7-oxo-7h-dib... 2 3
Adenosine receptor A3 and Adenosine receptor A1 ligand propyl ... 6 63
5-hydroxytryptamine receptor 3E and 5-hydroxytryptamine recept... 10 4
NS5B protein inhibitor AC1NQMYG family 6 12
Muscarinic acetylcholine receptor M3 and Muscarinic acetylchol... 2 1
Cannabinoid receptor 2 ligand [(4R,4aS,8aR)-4-hydroxy-4-phenyl... 2 41
5-hydroxytryptamine receptor 1D and 5-hydroxytryptamine recept... 3 1
Corticosteroid 11-beta-dehydrogenase isozyme 1 inhibitor SureC... 4 7
Acetylcholinesterase inhibitor CHEMBL1651140 family 4 4
Cannabinoid receptor 2 and Cannabinoid receptor 1 ligand [(4S,... 5 2
Prostaglandin D2 receptor 2 ligand SureCN2189431 family 7 1
NS5B protein inhibitor AC1O5AET family 3 1
NS5B protein inhibitor AC1NQMYP family 5 0
5-hydroxytryptamine receptor 3A and 5-hydroxytryptamine recept... 9 6
Cannabinoid receptor 1 ligand N-[2-(cyclopropylamino)-2-oxoeth... 5 5
Egl nine homolog 1 inhibitor 2-[5-methyl-6-[[1-oxo-2-(4-phenyl... 4 3
Substance-P receptor ligand SureCN7796965 family 9 1
5-hydroxytryptamine receptor 4 ligand 4-[2-[4-[[(1-propan-2-yl... 1 1
Neuromedin-K receptor and Potassium voltage-gated channel subf... 13 2
Substance-P receptor ligand N-[[3,5-bis(trifluoromethyl)phenyl... 1 3
Substance-P receptor ligand AGN-PC-004REJ family 3 0
Platelet-activating factor receptor ligand SureCN9852997 family 1 1
D(3) dopamine receptor and D(2) dopamine receptor ligand AGN-P... 2 1
Peroxisome proliferator-activated receptor gamma ligand AGN-PC... 4 4
Glutamate carboxypeptidase 2 inhibitor 1-[(3-carboxyphenyl)met... 4 11


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00326306 CHEMBL1765267 Bioactive [(4S,4aR,8aS)-4-hydroxy-4-phenyl-2,3,4a,5,6,7,8,8a-octahydroquinolin-1-yl]-(6-methylpyridin-2-yl)methanone
CFAMM00326303 CHEMBL1765161 Bioactive [(4R,4aS,8aR)-4-hydroxy-4-phenyl-2,3,4a,5,6,7,8,8a-octahydroquinolin-1-yl]-quinolin-2-ylmethanone
CFAMM00326296 CHEMBL120668 Bioactive N-benzyl-3-(hydroxymethyl)-N-methyl-4-phenylquinoline-2-carboxamide

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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