CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM1677
Family Name Cysteinyl leukotriene receptor 1 ligand (2S)-3-[(1S)-3-(2-acetylphenyl)-1-[3-[(E)-2-(7-chloroquinolin-2-yl)ethenyl]phenyl]propyl]sulfanyl-2-methylpropanoic acid family
No. of Seeds 6 No. of Other Members 1
Family Centroid CFAMM00326316 Functional Category Bioactive
Superfamily Canalicular multispecific organic anion transporter 1 Inhibitor MK-571 Superfamily
Class Class 131

Cousin Family NamesSeedsMembers
Cysteinyl leukotriene receptor 1 Ligand Montelukast Family 37 29
Dihydroorotate dehydrogenase Inhibitor Brequinar Family 9 122
Canalicular multispecific organic anion transporter 1 Inhibito... 7 5
NS5B protein inhibitor AC1NQMYP family 5 0
Proline--tRNA ligase, cytoplasmic and Bifunctional glutamate/p... 1 6
Capsid scaffolding protein inhibitor 4-[[[5-[(E)-2-(7-chloroqu... 1 1


External ID

Functional Category

Molecule Name

CFAMM00326312 CHEMBL143639 Bioactive (2S)-3-[(1S)-1-[3-[(E)-2-(7-chloroquinolin-2-yl)ethenyl]phenyl]-3-(2-propanoylphenyl)propyl]sulfanyl-2-methylpropanoic acid
CFAMM00326311 CHEMBL142805 Bioactive (2S)-3-[(1S)-3-(3-acetylphenyl)-1-[3-[(E)-2-(7-chloroquinolin-2-yl)ethenyl]phenyl]propyl]sulfanyl-2-methylpropanoic acid
CFAMM00326318 CHEMBL142395 Bioactive (2S)-3-[(1S)-1-[3-[(E)-2-(7-chloroquinolin-2-yl)ethenyl]phenyl]-3-(2-formylphenyl)propyl]sulfanyl-2-methylpropanoic acid
CFAMM00326317 CHEMBL142627 Bioactive (2S)-3-[(1S)-1-[3-[(E)-2-(7-chloroquinolin-2-yl)ethenyl]phenyl]-3-(3-methoxycarbonylphenyl)propyl]sulfanyl-2-methylpropanoic acid
CFAMM00326316 CHEMBL141233 Bioactive (2S)-3-[(1S)-3-(2-acetylphenyl)-1-[3-[(E)-2-(7-chloroquinolin-2-yl)ethenyl]phenyl]propyl]sulfanyl-2-methylpropanoic acid
CFAMM00326315 CHEMBL120779 Bioactive (2S)-3-[(1S)-3-(2-benzoylphenyl)-1-[3-[(E)-2-(7-chloroquinolin-2-yl)ethenyl]phenyl]propyl]sulfanyl-2-methylpropanoic acid

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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