CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM16776
Family Name Calpain-1 catalytic subunit and Cathepsin B inhibitor N-(4-amino-3,4-dioxo-1-phenylbutan-2-yl)-1-(1-benzothiophene-2-carbonyl)piperidine-4-carboxamide family
No. of Seeds 1 No. of Other Members 0
Family Centroid CFAMM00439316 Functional Category Bioactive
Superfamily Cathepsin K and Caspase-1 Binder Superfamily
Class Class 3102

Cousin Family NamesSeedsMembers
Neuronal acetylcholine receptor subunit alpha-7 Ligand EVP-612... 1 11
72 kDa type IV collagenase Inhibitor Batimastat Family 6 52
Substance-K receptor ligand 6-methyl-N-[1-[[(2S)-5-[4-(oxan-4-... 21 7
Substance-K receptor ligand N-[1-[[(2S)-5-[4-(dimethylsulfamoy... 9 16
Growth hormone secretagogue receptor type 1 ligand 2-amino-N-[... 4 2
Histone deacetylase 1 and Potassium voltage-gated channel subf... 4 36
Sigma non-opioid intracellular receptor 1 ligand ST50280143 fa... 3 54
Gonadotropin-releasing hormone receptor ligand 3-[(2R)-2-amino... 3 1
Melanin-concentrating hormone receptor 1 ligand (3S)-3-[[5-(4-... 15 16
D(4) dopamine receptor and D(2) dopamine receptor ligand AGN-P... 9 7
Neuronal acetylcholine receptor subunit alpha-7 and 5-hydroxyt... 6 6
Growth hormone secretagogue receptor type 1 ligand (2S)-2,6-di... 2 1
D(3) dopamine receptor and D(2) dopamine receptor ligand N-[4-... 2 0
D(3) dopamine receptor and D(2) dopamine receptor ligand AGN-P... 4 3
Kappa-type opioid receptor and Mu-type opioid receptor ligand ... 1 2
Kappa-type opioid receptor ligand 2-[2-oxo-2-[(2S)-2-(pyrrolid... 2 1
Sodium-dependent noradrenaline transporter and Sodium-dependen... 5 5
5-hydroxytryptamine receptor 1A ligand (3R)-N-(1-adamantyl)-1,... 2 0
DNA-(apurinic or apyrimidinic site) lyase and Cytochrome P450 ... 1 1


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00439316 CHEMBL407974 Bioactive N-(4-amino-3,4-dioxo-1-phenylbutan-2-yl)-1-(1-benzothiophene-2-carbonyl)piperidine-4-carboxamide

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

27514 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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