CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM16798
Family Name Cyclin-dependent kinase 2 and Cyclin-dependent kinase 1 inhibitor GW305178X family
No. of Seeds 2 No. of Other Members 0
Family Centroid CFAMM00429002 Functional Category Bioactive
Superfamily Prelamin-A/C and Cyclin-dependent kinase 2 Binder Superfamily 2
Class Class 8

Cousin Family NamesSeedsMembers
5-hydroxytryptamine receptor 1B and 5-hydroxytryptamine recept... 14 2769
C-C chemokine receptor type 3 Ligand YM-344031 Family 19 106
Carbonic anhydrase 2 Inhibitor N-[2-(1h-indol-5-yl)-butyl]-4-s... 12 70
5-hydroxytryptamine receptor 6 Ligand 4-(1h-indol-1-ylsulfonyl... 7 79
cAMP-specific 3',5'-cyclic phosphodiesterase 4A and cAMP-speci... 3 29
Endothelin B receptor Ligand IRL-2500 Family 34 87
Gamma-aminobutyric acid receptor subunit alpha-1 and Gamma-ami... 12 72
Vasopressin V2 receptor Ligand YM-35278 Family 33 38
Gonadotropin-releasing hormone receptor ligand 1-(3-azabicyclo... 6 2
Histamine H3 receptor ligand AGN-PC-04YWRD family 5 13
Cellular tumor antigen p53 and Beta-lactamase inhibitor CHEMBL... 1 36
Prelamin-A/C and Pyruvate kinase PKM inhibitor CHEMBL1481187 f... 1 7
Neuropeptide Y receptor type 5 ligand 2-indol-1-yl-N-[4-[(prop... 7 6
Glutamate receptor ionotropic, NMDA 2B ligand N-[3-[2-(4-benzy... 2 0
Gonadotropin-releasing hormone receptor ligand SureCN7899418 f... 12 4
Hepatocyte growth factor receptor and Protein-tyrosine kinase ... 2 15
Cyclin-dependent kinase 2 and Cyclin-dependent kinase 1 inhibi... 2 2
Cyclin-dependent kinase 2 and Cyclin-dependent kinase 1 inhibi... 2 3
Tyrosine-protein kinase Yes and Proto-oncogene tyrosine-protei... 7 18


CFAM Mol ID

External ID

Functional Category

Molecule Name


Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

27260 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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