CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM168
Family Name Sigma non-opioid intracellular receptor 1 ligand AGN-PC-074TFC family
No. of Seeds 2 No. of Other Members 7
Family Centroid CFAMM00031145 Functional Category Bioactive
Superfamily D(1A) dopamine receptor and D(2) dopamine receptor Binder Superfamily
Class Class 2232

Cousin Family NamesSeedsMembers
Opioid receptor ligand opiate Levorphanol Family 18 537
D(1B) dopamine receptor Ligand Apomorphine Family 30 271
Muscarinic acetylcholine receptor M3 Ligand Tolterodine Family 8 171
Kappa-type opioid receptor Ligand Dezocine Family 36 46
Eptazocine Hbr family 6 8
Noradrenergic re-uptake and Opioid receptor Ligand Tapentadol ... 21 79
5-hydroxytryptamine receptor 1A Ligand (s)-uh-301 Family 35 20
Sodium-dependent dopamine transporter and Sodium-dependent nor... 9 16
D(2) dopamine receptor and D(1A) dopamine receptor Ligand 3-br... 2 1
Kappa-type opioid receptor and Mu-type opioid receptor Ligand ... 18 13
Squalene synthase Inhibitor 3-[7'-(methoxy)-napht-2'-yl]-quinu... 53 30
D(2) dopamine receptor and D(3) dopamine receptor Ligand D-237... 21 56
Delta-type opioid receptor and Kappa-type opioid receptor Liga... 44 3
Alpha-2A adrenergic receptor and Alpha-2B adrenergic receptor ... 3 4
Kappa-type opioid receptor Ligand Morphinan Cyclic Imine Analo... 3 1
Sigma non-opioid intracellular receptor 1 ligand AGN-PC-074TF5... 1 0
Estrogen receptor and Estrogen receptor beta ligand AGN-PC-01Z... 2 4
Sigma non-opioid intracellular receptor 1 ligand CHEMBL154452 ... 2 1
D(1A) dopamine receptor ligand (5R)-8-bromo-3-methyl-5-phenyl-... 6 15
D(1A) dopamine receptor and D(2) dopamine receptor ligand AGN-... 1 1
Mu-type opioid receptor and Kappa-type opioid receptor ligand ... 3 0
D(1A) dopamine receptor and D(2) dopamine receptor ligand Biom... 3 1
Kappa-type opioid receptor and Mu-type opioid receptor ligand ... 1 0
Glutamate receptor ionotropic, NMDA 1 and Glutamate receptor i... 2 2


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00308334 CHEMBL334350 Bioactive (1S)-6-bromo-2-methyl-1-phenyl-3,4-dihydro-1H-isoquinolin-7-ol

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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