CFam Chemical Families Database
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Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM16825
Family Name Collagenase 3 and Matrix metalloproteinase-9 inhibitor 1-acetyl-N-hydroxy-4-(4-methoxyphenyl)sulfonyl-3,5-dihydro-2H-1,4-benzodiazepine-3-carboxamide family
No. of Seeds 6 No. of Other Members 7
Family Centroid CFAMM00330450 Functional Category Bioactive
Superfamily Neutrophil elastase Inhibitor Sivelestat Sodium Hydrate Superfamily
Class Class 243

Cousin Family NamesSeedsMembers
Stromelysin-1 Inhibitor PG-530742 Family 4 23
Neutrophil elastase Inhibitor Sivelestat Sodium Hydrate Family 2 2
Leukotriene A-4 hydrolase Inhibitor N5-[4-(phenylmethoxy)pheny... 7 49
Disintegrin and metalloproteinase domain-containing protein 17... 82 411
Galanin receptor type 1 and Galanin receptor type 2 Ligand Gal... 55 132
Disintegrin and metalloproteinase domain-containing protein 17... 25 33
Matrix metalloproteinase-9 and Collagenase 3 inhibitor AGN-PC-... 2 55
Matrix metalloproteinase-9 and Collagenase 3 inhibitor 5-bromo... 7 1
Matrix metalloproteinase-9 and Collagenase 3 inhibitor 2-[benz... 9 9
Matrix metalloproteinase-9 and Collagenase 3 inhibitor methyl ... 1 0
72 kDa type IV collagenase and Matrix metalloproteinase-9 inhi... 2 7
Matrix metalloproteinase-9 and Collagenase 3 inhibitor 5-bromo... 2 1
Matrix metalloproteinase-9 and 72 kDa type IV collagenase inhi... 6 16
Matrix metalloproteinase-9 and Collagenase 3 inhibitor 4-benzy... 10 32
72 kDa type IV collagenase and Matrix metalloproteinase-9 inhi... 3 13
Disintegrin and metalloproteinase domain-containing protein 17... 2 8
Disintegrin and metalloproteinase domain-containing protein 17... 10 39
Collagenase 3 and Matrix metalloproteinase-9 inhibitor 4-acety... 9 4
Collagenase 3 and Matrix metalloproteinase-9 inhibitor (4R)-N-... 13 4
Collagenase 3 and Stromelysin-1 inhibitor 1-N-benzyl-3-N-hydro... 7 15
Pol polyprotein inhibitor AC1LAPRV family 13 7
Matrix metalloproteinase-9 and Collagenase 3 inhibitor N-hydro... 2 1
Matrix metalloproteinase-9 and Collagenase 3 inhibitor AGN-PC-... 7 12
Cellular tumor antigen p53 and Microtubule-associated protein ... 1 12
Lethal(3)malignant brain tumor-like protein 1 inhibitor CHEMBL... 1 5
Pol polyprotein inhibitor AC1LAGJO family 6 1
Neutrophil collagenase and Stromelysin-1 inhibitor 7-[[(2S)-2-... 10 9
Neutrophil collagenase and Stromelysin-1 inhibitor AGN-PC-075O... 14 27
Pol polyprotein inhibitor AC1LA9K7 family 7 23
Collagenase 3 and 72 kDa type IV collagenase inhibitor (5R)-N-... 7 0
Neutrophil collagenase inhibitor (3R)-2-[4-[4-(dimethylamino)p... 2 4
Neutrophil collagenase and Stromelysin-1 inhibitor tert-butyl ... 2 0
72 kDa type IV collagenase and Collagenase 3 inhibitor (2R)-1-... 25 6
Collagenase 3 and 72 kDa type IV collagenase inhibitor (2R,4S)... 7 1
Collagenase 3 and 72 kDa type IV collagenase inhibitor (2R,4Z)... 17 0
Macrophage metalloelastase and 72 kDa type IV collagenase inhi... 7 4
Collagenase 3 and Disintegrin and metalloproteinase domain-con... 4 0
72 kDa type IV collagenase and Matrix metalloproteinase-9 inhi... 3 2
Disintegrin and metalloproteinase domain-containing protein 17... 25 5
Collagenase 3 and 72 kDa type IV collagenase inhibitor (2R)-2-... 4 6
Collagenase 3 and 72 kDa type IV collagenase inhibitor (2R)-2-... 2 0
Disintegrin and metalloproteinase domain-containing protein 17... 9 3
Disintegrin and metalloproteinase domain-containing protein 17... 3 3
Pol polyprotein inhibitor SureCN4637317 family 19 6
Bone morphogenetic protein 1 inhibitor 3-[[4-(benzylcarbamoyla... 1 9
Matrix metalloproteinase-9 and Neutrophil collagenase inhibito... 3 0
Alpha-1,6-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltra... 2 1
Matrix metalloproteinase-9 and 72 kDa type IV collagenase inhi... 20 23
Matrix metalloproteinase-9 and 72 kDa type IV collagenase inhi... 4 2
Collagenase 3 and Matrix metalloproteinase-9 inhibitor 1-benzy... 13 3
Disintegrin and metalloproteinase domain-containing protein 17... 4 17
Matrix metalloproteinase-9 and 72 kDa type IV collagenase inhi... 8 6
72 kDa type IV collagenase and Interstitial collagenase inhibi... 2 0
Neutrophil elastase inhibitor 2-[3-[(4-methoxyphenyl)sulfonyla... 1 0
Collagenase 3 and Matrix metalloproteinase-9 inhibitor 1-benzy... 6 2
Neutrophil collagenase and Interstitial collagenase inhibitor ... 3 0
Matrix metalloproteinase-9 and Collagenase 3 inhibitor AGN-PC-... 2 2
Collagenase 3 and Disintegrin and metalloproteinase domain-con... 1 0
Matrix metalloproteinase-9 and 72 kDa type IV collagenase inhi... 2 1
Collagenase 3 and Matrix metalloproteinase-9 inhibitor 3-N-hyd... 1 2
Collagenase 3 and Matrix metalloproteinase-9 inhibitor 1-benzo... 6 7
72 kDa type IV collagenase and Collagenase 3 inhibitor AGN-PC-... 3 2
72 kDa type IV collagenase and Collagenase 3 inhibitor 2-[[2-(... 2 0
Orexin receptor type 2 and Orexin receptor type 1 ligand AGN-P... 2 0
5-hydroxytryptamine receptor 2A and 5-hydroxytryptamine recept... 2 1
Collagenase 3 and Matrix metalloproteinase-9 inhibitor AGN-PC-... 2 1
Coagulation factor X inhibitor N-[1-[2-fluoro-4-(2-methylsulfo... 2 2
Elongation of very long chain fatty acids protein 6 inhibitor ... 2 7
Bone morphogenetic protein 1 inhibitor (2R)-5-[(2-chlorophenyl... 1 0


CFAM Mol ID

External ID

Functional Category

Molecule Name


Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

27511 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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