CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM16826
Family Name Endothelin-1 receptor and Endothelin B receptor ligand SureCN4631377 family
No. of Seeds 4 No. of Other Members 15
Family Centroid CFAMM00439486 Functional Category Bioactive
Superfamily Endothelin-1 receptor and Endothelin B receptor Binder Superfamily 14
Class Class 698

Cousin Family NamesSeedsMembers
Dihydropterin pyrophosphokinase-dihydropteroate synthase Inhib... 3 101
Endothelin-1 receptor Ligand Sitaxsentan Family 6 24
Endothelin-1 receptor Ligand BMS-182874 Family 6 10
Endothelin-1 receptor and Endothelin B receptor ligand N-[[2-[... 1 0
Endothelin-1 receptor ligand 3-[(4-chloro-3-methyl-1,2-oxazol-... 7 22
Endothelin-1 receptor ligand N-(4-chloro-3-methyl-1,2-oxazol-5... 1 1
Endothelin-1 receptor ligand AGN-PC-0CZXAO family 21 5
Endothelin-1 receptor ligand 3-[(4-chloro-3-methyl-1,2-oxazol-... 2 2
Endothelin-1 receptor and Endothelin B receptor ligand AGN-PC-... 1 10
Endothelin-1 receptor and Endothelin B receptor ligand SureCN4... 3 3
Endothelin-1 receptor ligand AGN-PC-043ARO family 3 2
Endothelin-1 receptor and Endothelin B receptor ligand SureCN7... 2 24
Endothelin-1 receptor ligand SureCN4631365 family 2 1


External ID

Functional Category

Molecule Name

CFAMM00439503 CHEMBL47424 Bioactive SureCN4630589
CFAMM00439486 CHEMBL445101 Bioactive SureCN4631377
CFAMM00439500 CHEMBL47915 Bioactive SureCN4631360
CFAMM00439485 CHEMBL413093 Bioactive SureCN4632386

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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