CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM16855
Family Name Sigma non-opioid intracellular receptor 1 ligand (5S)-5-[[4-(1,3-benzodioxol-5-yl)-4-hydroxypiperidin-1-yl]methyl]-3-phenyl-1,3-oxazolidin-2-one family
No. of Seeds 4 No. of Other Members 18
Family Centroid CFAMM00439625 Functional Category Bioactive
Superfamily Sigma non-opioid intracellular receptor 1 Binder Superfamily 8
Class Class 833

Cousin Family NamesSeedsMembers
Macrophage migration inhibitory factor Inhibitor 3-benzyl-5-me... 10 42
Alpha-1A adrenergic receptor and Alpha-1D adrenergic receptor ... 3 2
Neuropeptide S receptor and Survival motor neuron protein liga... 1 2
Sodium-dependent noradrenaline transporter and Sodium-dependen... 2 13
Sigma non-opioid intracellular receptor 1 ligand (5S)-5-[(4-hy... 1 5
Monoglyceride lipase and Fatty-acid amide hydrolase 1 inhibito... 1 1
Sodium channel protein type 9 subunit alpha ligand AGN-PC-0A9T... 3 3
Neuronal acetylcholine receptor subunit alpha-7 ligand (5R)-3-... 1 1


External ID

Functional Category

Molecule Name

CFAMM00439625 CHEMBL47774 Bioactive (5S)-5-[[4-(1,3-benzodioxol-5-yl)-4-hydroxypiperidin-1-yl]methyl]-3-phenyl-1,3-oxazolidin-2-one
CFAMM00439631 CHEMBL417353 Bioactive (5S)-5-[[4-(1,3-benzodioxol-5-yl)-4-hydroxypiperidin-1-yl]methyl]-3-[4-(cyclopropylmethoxy)phenyl]-1,3-oxazolidin-2-one
CFAMM00439622 CHEMBL45535 Bioactive (5S)-5-[[4-(1,3-benzodioxol-5-yl)-4-hydroxypiperidin-1-yl]methyl]-3-[4-(trifluoromethoxy)phenyl]-1,3-oxazolidin-2-one
CFAMM00439627 CHEMBL47715 Bioactive (5S)-5-[[4-(1,3-benzodioxol-5-yl)-4-hydroxypiperidin-1-yl]methyl]-3-(4-chlorophenyl)-1,3-oxazolidin-2-one

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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