CFam Chemical Families Database
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Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM16856
Family Name Sigma non-opioid intracellular receptor 1 ligand (5S)-5-[(4-hydroxy-4-phenylpiperidin-1-yl)methyl]-3-(4-methoxyphenyl)-1,3-oxazolidin-2-one family
No. of Seeds 1 No. of Other Members 5
Family Centroid CFAMM00439642 Functional Category Bioactive
Superfamily Sigma non-opioid intracellular receptor 1 Binder Superfamily 8
Class Class 833

Cousin Family NamesSeedsMembers
5-hydroxytryptamine receptor 1A and D(2) dopamine receptor Lig... 3 27
D(2) dopamine receptor Ligand Pardoprunox Family 4 81
5-hydroxytryptamine receptor 1A Ligand (s)-way 100135 Family 94 975
Muscarinic acetylcholine receptor M1 Ligand AC-260584 Family 4 36
CGMP-inhibited 3',5'-cyclic phosphodiesterase Inhibitor Cilost... 6 202
5-hydroxytryptamine receptor 1A Ligand NAN-190 Family 14 28
Leukotriene A-4 hydrolase Inhibitor N-benzyl-4-[(2r)-pyrrolidi... 6 40
5-hydroxytryptamine receptor 1A and Alpha-1A adrenergic recept... 18 12
Macrophage migration inhibitory factor Inhibitor 3-benzyl-5-me... 10 42
5-hydroxytryptamine receptor 1A and Sodium-dependent dopamine ... 9 79
Renin Inhibitor Ro-66-1168 Family 10 30
Bifunctional epoxide hydrolase 2 Inhibitor 1-(3-(3-morpholinop... 24 102
Galanin receptor type 1 and Galanin receptor type 2 Ligand Gal... 55 132
5-hydroxytryptamine receptor 1A and 5-hydroxytryptamine recept... 9 28
5-hydroxytryptamine receptor 1A and 5-hydroxytryptamine recept... 21 13
Amine oxidase [flavin-containing] A and Amine oxidase [flavin-... 2 7
Liver carboxylesterase 1 Inhibitor SCH-48375 Family 2 28
D(4) dopamine receptor and D(2) dopamine receptor ligand AGN-P... 2 1
Muscarinic acetylcholine receptor M1 and Muscarinic acetylchol... 4 2
Muscarinic acetylcholine receptor M1 and Muscarinic acetylchol... 1 2
Neuropeptide S receptor and Survival motor neuron protein liga... 1 2
Potassium voltage-gated channel subfamily H member 2 and Melan... 9 4
Muscarinic acetylcholine receptor M3 and Muscarinic acetylchol... 4 1
Histamine H3 receptor ligand 5-[4-[3-[(2R)-2-methylpyrrolidin-... 2 3
Translocator protein inhibitor [11C]DAA1106 family 15 2
Translocator protein inhibitor N-methyl-2-[2-oxo-5-[4-(trifluo... 9 3
Urotensin-2 receptor and Cytochrome P450 3A4 ligand 5-chloro-3... 2 1
Hormone-sensitive lipase inhibitor SureCN7553414 family 1 1
Sigma non-opioid intracellular receptor 1 ligand (5S)-5-[[4-(1... 4 18
Monoglyceride lipase and Fatty-acid amide hydrolase 1 inhibito... 1 1
Metabotropic glutamate receptor 2 ligand (5R)-3-[[4-(4-ethoxyp... 3 9
Neuronal acetylcholine receptor subunit alpha-7 ligand (5R)-3-... 1 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00439642 CHEMBL417357 Bioactive (5S)-5-[(4-hydroxy-4-phenylpiperidin-1-yl)methyl]-3-(4-methoxyphenyl)-1,3-oxazolidin-2-one

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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