CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM1686
Family Name Serine/threonine-protein kinase PLK1 and Cytochrome P450 2C9 inhibitor 3-[(1R)-1-(2-chlorophenyl)ethoxy]-5-[5-[1-[3-(dimethylamino)propyl]pyrazol-4-yl]benzimidazol-1-yl]thiophene-2-carboxamide family
No. of Seeds 7 No. of Other Members 0
Family Centroid CFAMM00133055 Functional Category Bioactive
Superfamily Serine/threonine-protein kinase PLK1 Inhibitor GSK461364 Superfamily
Class Class 875

Cousin Family NamesSeedsMembers
Serine/threonine-protein kinase PLK1 Inhibitor GSK461364 Family 40 84
Serine/threonine-protein kinase PLK1 and Serine/threonine-prot... 14 1
Serine/threonine-protein kinase PLK1 and Death-associated prot... 2 1
Serine/threonine-protein kinase PLK1 inhibitor SureCN2523858 f... 4 2


External ID

Functional Category

Molecule Name

CFAMM00326422 CHEMBL1208962 Bioactive 3-[(1R)-1-(2-chlorophenyl)ethoxy]-5-[5-[2-(2-methylsulfonylethylamino)pyridin-4-yl]benzimidazol-1-yl]thiophene-2-carboxamide
CFAMM00326421 CHEMBL1209015 Bioactive 3-[(1R)-1-(2-chlorophenyl)ethoxy]-5-[5-[1-(2-morpholin-4-ylethyl)pyrazol-4-yl]benzimidazol-1-yl]thiophene-2-carboxamide

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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