CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM1688
Family Name Sodium-dependent dopamine transporter and Sodium-dependent serotonin transporter inhibitor phenyl (1R,3S,4S)-3-(4-iodophenyl)-8-methyl-8-azabicyclo[3.2.1]octane-4-carboxylate family
No. of Seeds 4 No. of Other Members 1
Family Centroid CFAMM00301471 Functional Category Bioactive
Superfamily Sodium-dependent dopamine transporter and Sodium-dependent serotonin transporter Binder Superfamily 5
Class Class 2973

Cousin Family NamesSeedsMembers
Dopamine reuptake and Noradrenergic re-uptake Inhibitor Cocain... 13 136
Muscarinic acetylcholine receptor Ligand Methantheline Family 6 8
Mu-type opioid receptor Ligand Alvimopan Family 32 325
Sodium-dependent dopamine transporter Inhibitor Ioflupane I-12... 130 181
Sodium- and chloride-dependent GABA transporter 3 Inhibitor SN... 1 4
Squalene synthase Inhibitor 3-[7'-(methoxy)-napht-2'-yl]-quinu... 53 30
Sodium-dependent dopamine transporter Inhibitor (+/-)-threo-n-... 24 73
Sodium-dependent dopamine transporter Inhibitor (+/-)-threo-n-... 4 62
Sodium-dependent dopamine transporter and Muscarinic acetylcho... 2 1
Glutamate receptor ionotropic, kainate 2 ligand (2S,3S,4S)-4-[... 4 10
Sodium-dependent dopamine transporter and Transporter inhibito... 5 1
Sodium-dependent dopamine transporter and Sodium-dependent ser... 3 18
Sodium-dependent dopamine transporter and Transporter inhibito... 1 0
Sodium-dependent dopamine transporter and Sodium-dependent ser... 3 0
Sodium-dependent serotonin transporter and Transporter inhibit... 2 4
Sodium-dependent serotonin transporter and Sodium-dependent do... 3 2
Sodium-dependent dopamine transporter and Sodium-dependent ser... 5 1
Sodium-dependent serotonin transporter and Sodium-dependent do... 1 0
Transporter and Sodium-dependent dopamine transporter inhibito... 2 0
Histamine H1 receptor and 5-hydroxytryptamine receptor 2A liga... 4 1
Sodium- and chloride-dependent GABA transporter 1 inhibitor (3... 2 1
Mu-type opioid receptor and Kappa-type opioid receptor ligand ... 1 1
Putative NP ZINC04029215 Family 6 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00326438 CHEMBL126503 Bioactive AGN-PC-03WEHA

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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