CFam Chemical Families Database
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Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM16898
Family Name Coagulation factor X and Prothrombin inhibitor N,1-bis[(3-carbamimidoylphenyl)methyl]-3-chloroindole-2-carboxamide family
No. of Seeds 1 No. of Other Members 1
Family Centroid CFAMM00439803 Functional Category Bioactive
Superfamily Poly [ADP-ribose] polymerase 1 and Prothrombin Binder Superfamily
Class Class 1555

Cousin Family NamesSeedsMembers
5-hydroxytryptamine receptor 1B and 5-hydroxytryptamine recept... 14 2769
Hepatocyte growth factor receptor Ligand Arq 197 Family 10 400
Glycogen phosphorylase, muscle form Inhibitor PSN357 Family 3 253
Neuromedin-K receptor Ligand SB222200 Family 17 235
Cholecystokinin receptor type A Ligand Tarazepide Family 6 323
Receptor-type tyrosine-protein kinase FLT3 Inhibitor SU5614 Fa... 4 36
Poly [ADP-ribose] polymerase 1 Inhibitor AG-14699 Family 13 179
Reverse transcriptase Inhibitor IDX899 Family 2 118
Growth hormone receptor Ligand EP-51216 Family 34 390
Histone deacetylase 1 Inhibitor Panobinostat Family 5 93
D(3) dopamine receptor Ligand SB-277011 Family 13 178
Setipiprant family 5 118
CP-18770 family 6 27
C-C chemokine receptor type 3 Ligand YM-344031 Family 19 106
Lethal factor Inhibitor GM6001 Family 50 435
XL-888 family 16 85
Fibroblast growth factor receptor 2 Ligand Interferon Alfa (if... 14 162
Carbonic anhydrase 2 Inhibitor N-[2-(1h-indol-5-yl)-butyl]-4-s... 12 70
5-hydroxytryptamine receptor 1A and 5-hydroxytryptamine recept... 4 93
Acetylcholinesterase and Cholinesterase Inhibitor Lipocrine Fa... 18 36
Cholecystokinin receptor type A Ligand VL-0395 Family 12 117
Platelet-derived growth factor receptor alpha and Platelet-der... 3 3
Microsomal triglyceride transfer protein large subunit Inhibit... 5 9
Melanocortin receptor 3 and Melanocortin receptor 4 Ligand C[c... 20 18
14-alpha sterol demethylase Inhibitor CP-320626 Family 13 76
Kappa-type opioid receptor and Mu-type opioid receptor Ligand ... 19 108
cAMP-specific 3',5'-cyclic phosphodiesterase 4A and cAMP-speci... 3 29
Endothelin B receptor Ligand IRL-2500 Family 34 87
Amine oxidase [flavin-containing] A Inhibitor N-benzyl-1h-pyrr... 12 46
Gamma-aminobutyric acid receptor subunit alpha-1 and Gamma-ami... 12 72
Vasopressin V2 receptor Ligand YM-35278 Family 33 38
Acetylcholinesterase and Cholinesterase Inhibitor 7-oxo-7h-dib... 2 3
Acetylcholinesterase and Cholinesterase Inhibitor 3-(2-diethyl... 12 160
Melanocortin receptor Ligand Ac-his-dphe(3,4-dicl)-arg-trp-nh2... 10 14
Substance-P receptor ligand AGN-PC-01ZIXQ family 13 42
Huntingtin and Glycogen synthase kinase-3 beta inhibitor SB 21... 2 4
Cannabinoid receptor 1 ligand AGN-PC-04YSUM family 7 6
Sodium-dependent serotonin transporter and Sodium-dependent no... 2 0
Cellular tumor antigen p53 inhibitor CHEMBL1418224 family 1 62
Translocator protein inhibitor (2E)-N-(4-chlorophenyl)-N-methy... 2 13
Cellular tumor antigen p53 and Beta-lactamase inhibitor CHEMBL... 1 36
Thyroid hormone receptor beta and Microtubule-associated prote... 1 8
cGMP-specific 3',5'-cyclic phosphodiesterase and Dual 3',5'-cy... 4 129
Ceramide glucosyltransferase inhibitor AGN-PC-07YS0C family 4 3
Dipeptidyl peptidase 4 and Dipeptidyl peptidase 8 inhibitor 2-... 18 2
5-hydroxytryptamine receptor 1A and D(2) dopamine receptor lig... 3 2
Cannabinoid receptor 1 ligand 5-cyano-1-[(3,5-dichlorophenyl)m... 2 0
Cannabinoid receptor 1 ligand 5-cyano-N-(3-hydroxy-2,2-dimethy... 4 2
Substance-P receptor and Neuromedin-K receptor ligand SureCN88... 4 14
Coagulation factor X and Prothrombin inhibitor 2-carboxyindole... 2 8
Sodium-dependent serotonin transporter and 5-hydroxytryptamine... 2 1
Coagulation factor X inhibitor SureCN8289965 family 4 5
Cannabinoid receptor 1 ligand (2-cyclopentyl-5-prop-2-enyl-3,4... 3 8
Acetylcholinesterase and Cholinesterase inhibitor AGN-PC-009GH... 8 10
Histone deacetylase 6 and Histone deacetylase 1 inhibitor 4-[(... 3 5
Histone deacetylase 6 and Histone deacetylase 1 inhibitor 4-[(... 2 9
Cannabinoid receptor 1 ligand N-[2-(cyclopropylamino)-2-oxoeth... 5 5
Coagulation factor X inhibitor 3-chloro-N-[(1S,2S)-2-[[4-(2-ox... 22 3
Gonadotropin-releasing hormone receptor ligand 1-adamantyl-[2-... 3 1
Seprase and Prolyl endopeptidase inhibitor 7-chloro-N-[2-[(2S)... 3 3
Gonadotropin-releasing hormone receptor ligand SureCN7899418 f... 12 4
Dipeptidyl peptidase 9 and Dipeptidyl peptidase 8 inhibitor 3-... 17 0
Substance-P receptor ligand AGN-PC-004REJ family 3 0
Neuromedin-B receptor and Gastrin-releasing peptide receptor l... 2 0
Substance-P receptor and Substance-K receptor ligand N-methyl-... 2 2
Angiopoietin-1 receptor and Vascular endothelial growth factor... 1 0
KiSS-1 receptor ligand SureCN5132924 family 2 4
Poly [ADP-ribose] polymerase 1 inhibitor SureCN4998361 family 1 1
Translocator protein inhibitor N,N-dibutyl-2-(7-chloro-2-pheny... 3 1
D(3) dopamine receptor and D(2) dopamine receptor ligand AGN-P... 2 1
Translocator protein inhibitor 2-(7-Chloro-5-methyl-4-oxo-3-ph... 1 0
5-hydroxytryptamine receptor 7 ligand AGN-PC-00PFK0 family 1 0
Poly [ADP-ribose] polymerase 1 inhibitor SureCN3553433 family 22 0
Glycogen phosphorylase, liver form inhibitor 2-[(1R,2R)-2-[(5-... 3 2


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00439803 CHEMBL419704 Bioactive N,1-bis[(3-carbamimidoylphenyl)methyl]-3-chloroindole-2-carboxamide

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

24517 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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