CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM16929
Family Name Epidermal growth factor receptor ligand 4-Anilinopyrido[3,4-d]pyrimidine 20 family
No. of Seeds 2 No. of Other Members 0
Family Centroid CFAMM00439887 Functional Category Bioactive
Superfamily Epidermal growth factor receptor and Binder Superfamily
Class Class 202

Cousin Family NamesSeedsMembers
Transient receptor potential cation channel subfamily V member... 15 457
5-hydroxytryptamine receptor 1A and D(2) dopamine receptor Lig... 14 234
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subun... 35 270
GDC-0349 family 44 77
Epidermal growth factor receptor and Receptor tyrosine-protein... 11 138
Epidermal growth factor receptor Ligand PD-158780 Family 98 89
Epidermal growth factor receptor Ligand N*4*-(3-bromo-phenyl)-... 7 11
Epidermal growth factor receptor Ligand Benzo[g]quinazolin-4-y... 5 3
Epidermal growth factor receptor Ligand (3-bromo-phenyl)-quina... 7 5
Cyclin-dependent kinase 1 Inhibitor CGP-60474 Family 14 103
RAF proto-oncogene serine/threonine-protein kinase Inhibitor L... 219 124
Glycogen synthase kinase-3 beta Inhibitor 4-(5-bromo-1h-indol-... 7 18
Adenosine kinase inhibitor abt-702 family 14 1
Aurora kinase A inhibitor AGN-PC-07ZZEH family 2 4
cGMP-specific 3',5'-cyclic phosphodiesterase inhibitor AGN-PC-... 34 11
Adenosine kinase inhibitor 5-[3-(3-bromophenyl)propyl]-6-[2-(6... 3 0
Epidermal growth factor receptor ligand AGN-PC-076GVG family 8 1
Epidermal growth factor receptor ligand pyrido[4,3-d]pyrimidin... 11 0
Epidermal growth factor receptor ligand AGN-PC-076GXM family 6 0
Epidermal growth factor receptor ligand N-[4-(3-chloro-4-fluor... 8 4
Transient receptor potential cation channel subfamily V member... 4 0
Epidermal growth factor receptor ligand (2R,3R)-3-[[4-(3-bromo... 3 0
Epidermal growth factor receptor ligand AGN-PC-076GWD family 2 0
Epidermal growth factor receptor ligand Pyrroloquinazoline der... 7 0
Epidermal growth factor receptor ligand AGN-PC-078X7L family 4 0
Epidermal growth factor receptor ligand (E)-N-[4-(3-bromoanili... 2 1
Epidermal growth factor receptor ligand (E)-5-[4-(3-bromoanili... 11 0
Epidermal growth factor receptor ligand (E)-1-[4-(3-bromoanili... 9 0
Metabotropic glutamate receptor 1 ligand AGN-PC-00FV3S family 2 0
LIM domain kinase 1 and LIM domain kinase 2 inhibitor (2S)-N'-... 9 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00439887 CHEMBL422292 Bioactive 4-Anilinopyrido[3,4-d]pyrimidine 20
CFAMM00439886 CHEMBL453378 Bioactive ethyl (E)-5-[4-(3-bromoanilino)pyrido[3,4-d]pyrimidin-6-yl]-4-oxopent-2-enoate

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

27746 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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