CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM16935
Family Name 5-hydroxytryptamine receptor 1D and 5-hydroxytryptamine receptor 1B ligand SureCN8687843 family
No. of Seeds 1 No. of Other Members 0
Family Centroid CFAMM00256692 Functional Category Bioactive
Superfamily Prostaglandin E2 receptor EP3 subtype Ligand DG041 Superfamily
Class Class 867

Cousin Family NamesSeedsMembers
5-hydroxytryptamine receptor 1B ligand triptan Almotriptan Family 8 438
5-hydroxytryptamine receptor 1B and 5-hydroxytryptamine recept... 4 171
D(2) dopamine receptor Ligand Sertindole Family 3 173
Prostaglandin E2 receptor EP3 subtype Ligand DG041 Family 9 16
D(1B) dopamine receptor Ligand LE-300 Family 65 452
Platelet-derived growth factor receptor alpha and Platelet-der... 5 48
5-hydroxytryptamine receptor 6 Ligand E-6837 Family 22 44
Steroid 17-alpha-hydroxylase/17,20 lyase and Cytochrome P450 1... 7 16
Mitogen-activated protein kinase 14 Inhibitor 4-(2-ethyl-4-m-t... 14 41
Inosine-5'-monophosphate dehydrogenase 2 Inhibitor 3-(thiophen... 9 66
NF-kappa-B Inhibitor 5-bromo-n-(quinolin-8-yl)thiophene-2-sulf... 2 5
Sodium-dependent serotonin transporter Inhibitor 3-(3-aminocyc... 94 23
Histamine H3 receptor and Potassium voltage-gated channel subf... 6 14
Nuclear receptor ROR-gamma and Niemann-Pick C1 protein ligand ... 1 12
5-hydroxytryptamine receptor 2A and D(2) dopamine receptor lig... 2 4
Sodium-dependent serotonin transporter inhibitor SureCN9171444... 2 0
5-hydroxytryptamine receptor 1D and 5-hydroxytryptamine recept... 2 0
5-hydroxytryptamine receptor 6 ligand SureCN3147604 family 7 6
Sodium-dependent serotonin transporter inhibitor 3-[[(3S)-1-az... 1 1
5-hydroxytryptamine receptor 6 ligand 1-(4-chlorophenyl)sulfon... 8 4
5-hydroxytryptamine receptor 6 ligand 1-(5-bromothiophen-2-yl)... 4 0
5-hydroxytryptamine receptor 6 ligand 2-methyl-5-methylsulfany... 1 1
Epidermal growth factor receptor and Vascular endothelial grow... 14 19
5-hydroxytryptamine receptor 6 ligand 3,4-dichloro-N-[3-[[(2R)... 5 0
Protein kinase C theta type and Protein kinase C delta type in... 4 5
5-hydroxytryptamine receptor 6 and Cytochrome P450 3A4 ligand ... 1 0
Prostaglandin E2 receptor EP3 subtype ligand N-(4,5-dichloroth... 3 0


CFAM Mol ID

External ID

Functional Category

Molecule Name


Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

26843 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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