CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM16943
Family Name Prothrombin inhibitor [(1R)-4-carbamimidoylsulfanyl-1-[[2-[methyl(3-phenylpropanoyl)amino]acetyl]amino]butyl]boronic acid family
No. of Seeds 1 No. of Other Members 0
Family Centroid CFAMM00439936 Functional Category Bioactive
Superfamily Prothrombin and Neuromedin-K receptor Binder Superfamily
Class Class 1362

Cousin Family NamesSeedsMembers
Vasopressin V1a receptor Ligand Felypressin Family 12 820
Alpha-1B adrenergic receptor Ligand Lisdexamfetamine Family 14 443
Angiotensin-converting enzyme Inhibitor Spirapril Family 17 86
Melanocortin receptor 4 Ligand Ro-27-3225 Family 6 52
Dipeptidyl peptidase 4 Inhibitor Denagliptin Family 24 151
72 kDa type IV collagenase Inhibitor Batimastat Family 6 52
Prothrombin Inhibitor Efegatran Family 9 47
Neuromedin-K receptor Ligand Senktide Family 15 22
Neuromedin-K receptor Ligand PD-157672 Family 9 37
Cathepsin K and Cathepsin L1 Inhibitor N-benzoyl-phenylalanyl-... 13 77
Cathepsin B and Cathepsin S Inhibitor Ac-hphe-leu-ala-leuvsme ... 17 51
Delta-type opioid receptor and Kappa-type opioid receptor Liga... 3 21
Substance-P receptor Ligand [sar9,met(o2)11]-sp Family 34 9
Genome polyprotein Inhibitor Acasp-glu-met-glu-cha-cys Family 3 6
Genome polyprotein Inhibitor Acdif-ile-cha-cys Family 37 96
Prolyl endopeptidase Inhibitor SUAM-1221 Family 42 47
Aminopeptidase N Inhibitor 2-cinnamamido-n4-hexyl-n1-hydroxysu... 24 8
Prothrombin and Coagulation factor X inhibitor AGN-PC-074UE2 f... 1 0
Dipeptidyl peptidase 4 inhibitor (3S)-4-[(3R)-3-amino-4-(2,4,5... 1 1
Dipeptidyl peptidase 4 and Dipeptidyl peptidase 2 inhibitor (3... 2 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00439936 CHEMBL423259 Bioactive [(1R)-4-carbamimidoylsulfanyl-1-[[2-[methyl(3-phenylpropanoyl)amino]acetyl]amino]butyl]boronic acid

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

27668 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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