CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM16966
Family Name Alpha-2C adrenergic receptor and Alpha-2A adrenergic receptor ligand [(3R,3aS)-3-[[4-[(E)-2-methyl-3-phenylprop-2-enyl]piperazin-1-yl]methyl]-3a,4-dihydro-3H-chromeno[4,3-c][1,2]oxazol-7-yl] pyridine-4-carboxylate family
No. of Seeds 1 No. of Other Members 7
Family Centroid CFAMM00440029 Functional Category Bioactive with Natural Product
Superfamily Reverse transcriptase and Hemoglobin subunit alpha Binder Superfamily
Class Class 1002

Cousin Family NamesSeedsMembers
Oxytocin receptor and Vasopressin V1a receptor Ligand L-372662... 31 23
Acetylcholinesterase and Butyrylcholinesterase inhibitor [3-[[... 3 68
Endothelin-1 receptor ligand SureCN8118632 family 4 5
Sodium-dependent serotonin transporter and Alpha-2C adrenergic... 2 2


External ID

Functional Category

Molecule Name

CFAMM00440029 CHEMBL425324 Bioactive [(3R,3aS)-3-[[4-[(E)-2-methyl-3-phenylprop-2-enyl]piperazin-1-yl]methyl]-3a,4-dihydro-3H-chromeno[4,3-c][1,2]oxazol-7-yl] pyridine-4-carboxylate

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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